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    Did you mean ERK Pathway?
    Glossary ERK Pathway

    chain of proteins transmitting signals from cell surface to DNA

    The ERK Pathway, also known as the Extracellular Signal-Regulated Kinase Pathway, is a chain of proteins in the cell that communicates signals from a receptor on the cell's surface to the DNA in the nucleus. This pathway plays a crucial role in regulating various cellular activities, including growth, division, and differentiation. It is particularly important in the context of hair biology, as disruptions in this pathway can influence hair growth and contribute to conditions like alopecia.

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    1. Lactoferrin promotes hair growth in mice and increases dermal papilla cell proliferation through Erk/Akt and Wnt signaling pathways Archives of Dermatological Research · 2019 · 18 citations
    2. Extremely Low-Frequency Electromagnetic Fields Increase the Expression of Anagen-Related Molecules in Human Dermal Papilla Cells via GSK-3β/ERK/Akt Signaling Pathway International Journal of Molecular Sciences · 2020 · 7 citations
    3. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    4. Bacillus/Trapa japonica Fruit Extract Ferment Filtrate enhances human hair follicle dermal papilla cell proliferation via the Akt/ERK/GSK-3β signaling pathway BMC Complementary and Alternative Medicine · 2019 · 10 citations
    5. Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways Journal of Cosmetic Dermatology · 2013 · 39 citations
    6. CD271 orchestrates skin structure, differentiation, and inflammation via PI3K/Akt and PKCα/ERK pathways Cell Death and Disease · 2025
    7. Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts Molecular & cellular proteomics · 2019 · 9 citations
    8. The antimycotic agent clotrimazole inhibits melanogenesis by accelerating ERK and PI3K-/Akt-mediated tyrosinase degradation Experimental Dermatology · 2015 · 15 citations
    9. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    10. Norgalanthamine Stimulates Proliferation of Dermal Papilla Cells <i>via</i> Anagen-Activating Signaling Pathways Biological & Pharmaceutical Bulletin · 2018 · 5 citations
    11. Methanol Extract of Peach Kernel Induces Human Hair Follicle Dermal Papilla Cell Proliferation via the Extracellular Signal-Regulated Kinase Signaling Pathway Indian Journal of Pharmaceutical Sciences · 2024
    12. Insulin-like Growth Factor 1 (IGF-1) in Hair Regeneration: Mechanistic Pathways and Therapeutic Potential Current Issues in Molecular Biology · 2025
    13. Hair growth‐promotion effects of different alternating current parameter settings are mediated by the activation of Wnt/<i>β</i>‐catenin and MAPK pathway Experimental Dermatology · 2015 · 27 citations
    14. Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules · 2020 · 25 citations
    15. Mackerel-Derived Fermented Fish Oil Promotes Hair Growth by Anagen-Stimulating Pathways International Journal of Molecular Sciences · 2018 · 14 citations
    16. Human platelet lysate versus minoxidil stimulates hair growth by activating anagen promoting signaling pathways Biomedicine & Pharmacotherapy · 2016 · 11 citations
    17. Wheat Sprout Extract Stimulates Cell Proliferation via Phosphorylation of ERK and Akt in Human Dermal Papilla Cells 2017
    18. miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades Journal of Advanced Research · 2024 · 15 citations
    19. Stress-induced senescence of dermal papilla cells restored by synthesized ceramide 2017
    20. 277 Stress-induced senescence of dermal papilla cells restored by synthesized ceramide Journal of Investigative Dermatology · 2017
    21. Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation BioMed Research International · 2019 · 4 citations
    22. The Muscarinic Acetylcholine Receptor in Dermal Papilla Cells Regulates Hair Growth International Journal of Molecular Sciences · 2026
    23. The muscarinic acetylcholine receptor in dermal papilla cells regulates hair growth 2024
    24. Black Ginseng Concentrate Restores Hair Loss-Associated Dysfunction in Human Follicle Dermal Papilla Cells International Journal of Molecular Sciences · 2026
    25. Hair Growth-Promoting Effects of Astragalus sinicus Extracts in Human Follicle Dermal Papilla Cells Cosmetics · 2025
    26. Hair Growth Effect and the Mechanisms of Rosa rugosa Extract in DHT-Induced Alopecia Mice Model International Journal of Molecular Sciences · 2024
    27. Ginseng-derived nanoparticles induce skin cell proliferation and promote wound healing Journal of Ginseng Research · 2022 · 112 citations
    28. Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles Journal of Medicinal Food · 2014 · 49 citations
    29. Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells FEBS Open Bio · 2026
    30. AIMP1-Derived Peptide Secreted from Hair Follicle Stem Cells Promotes Hair Growth by Activating Dermal Papilla Cells International Journal of Biological Sciences · 2024 · 5 citations