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Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.

Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Trichoblastomas in rabbits are linked to uncontrolled embryonic hair growth and have distinct histological features.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

Skin cysts might help advance stem cell treatments to repair skin.

The author felt excited and honored to receive the 2016 Early Career Life Scientist Award.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

ΔNp63α helps control a protein that stops cancer cells from spreading.

Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.

Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

The document concludes that there have been significant improvements in diagnosing and treating skin diseases, including melanoma, with new techniques and therapies.

The gene Msx2 is crucial for hair follicle regeneration during wound healing.

Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.

The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.

Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Finasteride helps hair growth by decreasing cell death in hair follicles.

Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.

Ayurvedic remedies may boost immunity and balance in cancer treatment but need more research.