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    Glossary Epigenome

    chemical modifications to DNA and histones regulating gene expression

    The epigenome consists of chemical modifications to DNA and histone proteins that regulate gene expression without altering the underlying DNA sequence. These modifications can be influenced by environmental factors and can affect how genes are turned on or off, playing a crucial role in development, disease, and even conditions like alopecia.

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    Research 30 of 368

    1. The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome Nutrition reviews · 2008 · 231 citations
    2. The Transcriptomics and Epigenomics of Hair Follicles Updates in clinical dermatology · 2024
    3. Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging Scientific Reports · 2021 · 12 citations
    4. Maternal iron status in early pregnancy and DNA methylation in offspring: an epigenome-wide meta-analysis Clinical Epigenetics · 2022
    5. Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging Frontiers in Cell and Developmental Biology · 2022 · 7 citations
    6. Badanie roli zmienności genetycznej i epigenetycznej w starzeniu się skóry twarzy i włosów głowy oraz genetyczna predykcja związanych z wiekiem cech wyglądu człowieka Jagiellonian University Repository (Jagiellonian University) · 2024
    7. A State-of-the-Art Overview on (Epi)Genomics and Personalized Skin Rejuvenating Strategies Pharmaceutics · 2025
    8. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016 · 174 citations
    9. Identifying critical cell types and gene regulatory pathways for hair and skin disease Nature Genetics · 2023
    10. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    11. Genome assembly and methylome analysis of the white wax scale insect provides insight into sexual differentiation of metamorphosis in hexapod 2020
    12. Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging Frontiers in Cell and Developmental Biology · 2021 · 9 citations
    13. Differential distribution of the epigenetic marker 5‐hydroxymethylcytosine occurs in hair follicle stem cells during bulge activation Journal of Cutaneous Pathology · 2019 · 4 citations
    14. Transcriptional Control of Epidermal Stem Cells Advances in Experimental Medicine and Biology · 2013 · 4 citations
    15. Research Progress on the Molecular Mechanism of Poultry Feather Follicle Development Current Issues in Molecular Biology · 2025
    16. Tuberculosis mimicking the onset of systemic lupus erythematosus flare: Case based review International Journal of Rheumatic Diseases · 2023 · 1 citations
    17. Dynamics and Epigenetics of the Epidermal Differentiation Complex Epigenomes · 2024
    18. The Role of Histone Demethylases in Disease Springer eBooks · 2011 · 1 citations
    19. Epigenetic control of adult stem cell function Nature Reviews Molecular Cell Biology · 2016 · 179 citations
    20. Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations Scientific reports · 2018 · 58 citations
    21. Sexually dimorphic sail feathers in the Mandarin duck as a model for lifelong developmental modulation Scientific Reports · 2025 · 1 citations
    22. Facial skin aging: an integrative analysis of genetics, epigenetics, and lifestyle factors GeroScience · 2025
    23. Contaminants of emerging concern in the fetal environment 2022
    24. Clinical-exome sequencing unveils the genetic landscape of polycystic ovarian syndrome (PCOS) focusing on lean and obese phenotypes: implications for cost-effective diagnosis and personalized treatment Scientific Reports · 2024 · 13 citations
    25. Vitamin D, Lipid Metabolism and Prostate Cancer Trepo - Institutional Repository of Tampere University · 2009 · 1 citations
    26. Timing of expression of the core clock gene <i>Bmal1</i> influences its effects on aging and survival Science Translational Medicine · 2016 · 237 citations
    27. Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells Proceedings of the National Academy of Sciences of the United States of America · 2017 · 92 citations
    28. Next generation human skin constructs as advanced tools for drug development Experimental Biology and Medicine · 2017 · 69 citations
    29. The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells Nature Communications · 2021 · 50 citations
    30. Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart Cardiovascular Research · 2020 · 47 citations