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A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.

The skin and mucous membranes can regenerate over the basement membrane after damage, using nearby surviving cells.

Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

The upper dermal sheath can regenerate hair in rats.

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

Hormones and stretching both needed for nipple area skin growth in mice.

The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.

Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.

The document concludes that wound healing leads to skin repair or scar formation.

Krox20 overexpression in fibroblasts may play a role in abnormal scar formation and could be a target for new treatments.

Injecting follicular cells into skin can lead to the formation of new hair follicles.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Researchers created a potential skin substitute using a biodegradable mat that supports skin cell growth and layer formation.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.

Cystatin M/E helps in the final stages of hair and nail formation by controlling certain enzymes.

The treatment successfully integrated hair follicles into a dermal template, showing new hair growth and blood vessel formation.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

Island grafts can help study skin regeneration separately from other healing processes.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

Fish oil improves skin health in people with diabetes and high cholesterol.

The study suggests a link between varicella-zoster virus and segmental vitiligo, with evidence of the virus disrupting skin pigment cells.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.