2 citations
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January 1993 This study found that human trichohyalin has a unique protein sequence potentially contributing to at least three important functions in hair follicle and epidermal cells.
August 2023 in “Micromachines” In this study, researchers developed a multilayered gel bead culture model using a microgel-spotting device, successfully mimicking the early development of skin appendages and supporting in vitro hair follicle regeneration with structures resembling native hair follicles.
April 2023 in “Journal of Investigative Dermatology” In this study, researchers observed distinct aging signatures in mouse keratinocytes, with increased expression in older mice, and noted relevant pathway changes that were also evident in human skin, suggesting potential insights into intrinsic skin aging.
This study examined prenatal and postnatal development of rat skin, observing marked changes in epidermal thickness and collagen fiber distribution as the rats aged.
January 2009 in “한국피부장벽학회지” This study reports that in mice, CaR plays a critical role in sensing the epidermal Ca2+ gradient, influencing keratinocyte differentiation, and affecting epidermal development.
October 2024 in “International Journal of Comprehensive Veterinary Research.” In this study, researchers examined the skin of neonatal rabbits and found that most hair follicles were in the terminal stage, with hair shafts protruding through the epidermis, but noted the absence of sweat glands.
94 citations
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October 1994 in “The Journal of Cell Biology” This study demonstrates that overexpression of K16 in transgenic mice disrupts normal keratinization, leading to hyperkeratosis, acanthosis, and alterations in the skin's epithelial cells.
January 2026 in “British Journal of Dermatology” This study suggests that ELF5 plays a crucial role as a regulator and maintainer of stem/progenitor cell functions, impacting normal skin development and homeostasis.
426 citations
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August 2014 in “Nature Medicine” This narrative review examines the interactions between skin stem cells and their niches, finding new insights from advancements in genetic and imaging tools but reporting no new experimental results.
87 citations
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February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
70 citations
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November 1984 in “Cell & tissue research/Cell and tissue research” Vitamin D3 affects cell differentiation in specific skin areas.
13 citations
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June 2020 in “Scientific reports” In this study, melatonin administration enhanced various cellular and structural features of the scrotal skin in Soay rams, including increased thickness, cell count, and gland activity.
10 citations
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September 2023 in “Metabolites” This study reviews iron metabolism in the skin, highlighting how differentially expressed genes regulate iron recycling in the epidermis, and discusses changes in iron metabolism related to skin diseases.
7 citations
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January 1998 in “EXPERIMENTAL ANIMALS” This study found no significant differences in lectinhistochemical characteristics of the dorsal skin epidermis between hypotrichotic WBN/Ila-Ht rats and Wistar rats, except for varying lectin binding intensity.
6 citations
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August 1975 in “Journal of Endocrinology” This study found that cortisol and corticosterone led to thinning of the epidermis and hair follicle regression in fetal mouse skin, while testosterone promoted differentiation and sebaceous gland development.
5 citations
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April 2022 in “Cell Biology International” This study found that JAM-A modification in mouse wound models significantly promoted wound healing and fibroblast proliferation, potentially linked to increased levels of growth factors bFGF and EGF.
1 citations
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January 2024 in “Microorganisms” This study suggests that the synthetic peptide SPIKENET (SPK) may protect against long-term skin alterations in mice following coronavirus infection, offering potential therapeutic intervention for similar effects in humans post-COVID-19.
June 2015 in “OhioLink ETD Center (Ohio Library and Information Network)” This study found that acute UVB exposure in mice increases the synthesis of retinoic acid in the epidermis, which is necessary for normal repair from UVB light.
This study explored the carbohydrate composition of plasma cell membranes in human embryonic epidermis over various gestational ages and found specific patterns that may inform future diagnostic and therapeutic approaches for dermatoses.
43 citations
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January 2012 in “Biological Research” This review discusses the embryonic origins and characteristics of various stem cell populations in the skin, but it provides no new experimental results.
21 citations
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October 2007 in “Journal of Investigative Dermatology” Fetuin-A helps wounds heal without scars by promoting cell movement.
4 citations
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October 2017 in “Advances in tissue engineering & regenerative medicine” In this study, a bioengineered construct using a biodegradable polycaprolactone mat cocultured with human keratinocyte and rabbit dermal fibroblast cells demonstrated potential as a tissue-engineered skin substitute, showing good cell adhesion and growth.
3 citations
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study revealed key cellular dynamics and interactions during early embryonic mouse skin development, highlighting complex transitions from precursor states to diverse multilayered structures.
140 citations
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January 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This review discusses the application of liposomes in dermatology, highlighting their therapeutic value for drug stabilization, skin penetration enhancement, and treatment of hair follicle-associated disorders, but reports no new clinical results.
58 citations
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December 2000 in “Experimental Dermatology” This study found that new rabbit antisera against recombinant mouse involucrin effectively marked keratinocyte differentiation, with comparable expression patterns to human involucrin.
56 citations
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July 2004 in “Mechanisms of Development” Pax9 is crucial for proper tongue surface development and preventing skin-like changes.
44 citations
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May 2008 in “Acta Zoologica” This study explains how the development of keratin-associated proteins in embryonic epidermis is crucial for forming protective barriers in vertebrates, enabling them to adapt to terrestrial environments.
37 citations
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July 2016 in “Current Opinion in Cell Biology” This review summarizes recent discoveries about how tissue-resident stem cells interact with their environments during normal conditions and after injury, without reporting new results.
35 citations
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July 2010 in “The FEBS journal” In this study, researchers identified a highly reactive, isozyme-specific sequence for TGase 3, contributing to understanding its distinct functional role and activity distribution in the mouse epidermis.
30 citations
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January 1994 in “Micron” This study found that the formation of the fibre cuticle surface in Merino sheep is similar to the epidermal stratum corneum process and not from a modified plasma membrane as previously thought.