45 citations,
February 2001 in “Joint bone spine” Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
32 citations,
August 1999 in “Journal of Investigative Dermatology” Early onset hair loss linked to genetics and androgen levels.
30 citations,
July 2010 in “Experimental Dermatology” Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
23 citations,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
20 citations,
February 2013 in “Nutrition” Selenium-enriched green tea might be a safe prebiotic for gut health.
17 citations,
October 2003 in “Brazilian Journal of Medical and Biological Research” The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
13 citations,
May 2021 in “Plants” The leaf extract of Leea indica may reduce inflammation, dissolve blood clots, and promote hair growth.
11 citations,
April 2018 in “Nutrition Research” Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.
11 citations,
December 2014 in “The American journal of pathology” A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
10 citations,
May 2019 in “International Journal of Environmental Research and Public Health” Finasteride may cause kidney damage.
7 citations,
July 2021 in “Molecules/Molecules online/Molecules annual” The method can measure vitamin B3 levels in human hair accurately.
7 citations,
April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.
6 citations,
August 2015 in “Journal of Molecular Histology” Caspase-7 has functions in skin and hair that are not related to cell death.
6 citations,
October 1993 in “Endocrinology” Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
5 citations,
March 2023 in “Archives of dermatological research” Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
5 citations,
December 1942 in “Journal of the American Medical Association” Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.
2 citations,
July 2018 in “Elsevier eBooks” Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
2 citations,
January 2018 in “Biology and medicine” High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
1 citations,
February 2022 in “Open Access Macedonian Journal of Medical Sciences” Low zinc levels might contribute to early hair graying.
1 citations,
January 2014 in “Elsevier eBooks” Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
Vitamin D is crucial for skin health and managing skin diseases.
May 2022 in “Gastroenterology” Targeting NETs may help reduce fibrosis in Crohn's disease.
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
January 2017 in “Journal of clinical & experimental dermatology research” Low ferritin levels might be linked to telogen effluvium, but vitamin D levels are not.
September 2016 in “Journal of Dermatological Science” A gene mutation worsens skin irritation in mice due to a lack of certain fats.
January 2012 in “Methods in pharmacology and toxicology” TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
67 citations,
May 2018 in “Journal of Ginseng Research” Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.
34 citations,
March 2020 in “BMC plant biology” Graphene oxide and indole-3-acetic acid together inhibit root growth in Brassica napus L. by affecting multiple plant hormone pathways.
11 citations,
May 2009 in “Medical Hypotheses” Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
January 2019 in “Springer Reference Medizin” Follicle Stimulating Hormone is important for fertility.