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Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.

Scientists created a new 3D skin model from cells of plucked hairs that works like real skin and is easier to get.

Oxidative stress contributes to hair graying and loss as we age.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Aging causes changes in scalp cells that can negatively affect hair health.

Researchers found a new way to isolate sweat glands from the scalp for study and culture.

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Hair sunscreens are important for maintaining hair's cosmetic value.

Diet changes can help reduce acne by limiting certain hormones.

Oxidative stress increases in early hair loss, and family history plays a role; antioxidants may help future treatments.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Oxidative stress plays a role in female pattern baldness, causing an imbalance between harmful and protective elements in the body.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.

Men with male pattern baldness may have a higher risk of heart disease due to increased levels of a specific lipid in their blood.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.