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ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.

Certain gene variations are found in people with polycystic ovary syndrome.

Women with PCOS have more insulin resistance and are more likely to have heart-related health issues, with insulin resistance being a bigger factor than β-cell problems.

Spironolactone may help reduce hair loss in androgenic alopecia.

Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.

Imaging helps detect adrenal gland issues and monitor treatment in congenital adrenal hyperplasia, and can identify tumors affecting fertility.

A postmenopausal woman's excess male hormone symptoms were caused by a rare adrenal gland tissue in her ovary.

Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.

Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.

Alopecia is not a significant predictor of thyroid disease when age and sex are considered.

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.

The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.

Early balding, premature graying, and hair thinning can predict heart disease in young Asian males.

A hidden autoimmune syndrome was found during a shock, showing thyroid, adrenal, and ovarian issues.

The most common skin issues in females with Polycystic Ovary Syndrome (PCOS) are excessive hair growth, hair loss, oily skin, acne, dark skin patches, and skin tags, which may be linked to hormone and insulin levels.

The document concludes that hair loss and acne in women can be due to both androgen-related and unrelated causes, requiring a collaborative treatment approach.

Hirsutism can be treated with medications or hair removal methods, tailored to each person.

Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.

People with alopecia have a higher risk of thyroid cancer.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Hormones significantly affect skin health, with vitamin D playing a key role.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Older men with lower levels of available testosterone are more likely to be frail.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.