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Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Men with early hair loss and certain health factors may have a higher risk of developing reproductive issues, similar to polycystic ovary syndrome in women.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Excessive hair growth in women can be treated with medications like spironolactone and finasteride, and male-pattern baldness in women can be improved with similar treatments.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Exposure to plastics may increase the risk of irregular menstrual cycles and symptoms of hormone imbalance in teenage girls.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Old World monkeys are important for research but require proper social housing and welfare to ensure valid results and minimize stress.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

New hormonal therapies can help treat advanced prostate cancer but may cause testicular issues.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

Hair growth-promoting nutraceuticals do not block the cancer-fighting effects of tamoxifen and may enhance its action.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Autoimmune polyglandular syndrome can cause temporary brain issues that may improve on their own.

The safety of placental and umbilical extracts in cosmetics is uncertain, requiring more research.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Skin diseases can greatly affect daily life and require careful treatment and medication review.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

The document concludes that AFA should be considered in patients with acromegaly-like features but normal hormone levels, and more cases need to be identified to understand the condition fully.

A holistic treatment approach, including yoga, diet, exercise, and mindfulness, can effectively manage PCOS symptoms.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The treatment for alopecia areata with diphenylcyclopropenone was unsuccessful.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

Patients on mood stabilizers need regular health checks, but many aren't monitored properly.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.