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People with Lichen planopilaris are more likely to have certain autoimmune and endocrine disorders but less likely to have conditions like allergies and diabetes.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.

Serenoa repens may cause early puberty and should be used cautiously in children.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.

Women with nonclassical congenital adrenal hyperplasia may have a higher risk of fertility issues and miscarriages, and should get genetic counseling.

The document suggests that male hormones likely affect hair growth and baldness, and future treatments might involve stem cells and androgen-independent cells.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

The commentary suggests that certain hair and skin care products may be linked to frontal fibrosing alopecia, but not sunscreens, and calls for more thorough research on the causes.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Male rats grow hair faster than females, and certain hormones can slow or slightly increase hair growth, but not significantly beyond natural rates.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

Peginterferon alfa-2b and ribavirin therapy for hepatitis C can cause serious side effects, some different from those reported in clinical trials.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Canine hypothyroidism can be linked to diabetes, requiring thorough testing for proper diagnosis.

Polycystic ovaries are defined by having 12 or more small follicles in each ovary and are found in up to 33% of women, while Polycystic Ovary Syndrome (PCOS) is the most common hormone disorder in women of reproductive age, potentially increasing risk of obesity, diabetes, and heart diseases.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

High insulin levels are more common and a better predictor of carbohydrate issues in women with PCOS than glucose tolerance tests.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

The document outlines a method for diagnosing hair loss and suggests specific treatments based on the diagnosis.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

Both finasteride and metformin effectively treat PCOS by reducing hormone levels and insulin resistance.