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Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Finasteride reduces Hidradenitis Suppurativa flare-ups in children and teens, but long-term safety is unknown.

SHBG may be a useful early indicator and treatment target for PCOS.

EGFR-TKIs can cause significant skin, nail, and organ side effects.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Hidradenitis suppurativa improves with antiandrogen therapy.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.

Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Adrenal disorders can cause lasting brain and behavior issues in children.

The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Severe COVID-19 may cause hair loss, and doctors recommend supplements and topical treatments to manage it.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

The normal human prostate does not significantly affect blood DHT levels.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.