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    Glossary Endocannabinoid System

    complex cell-signaling system regulating mood, appetite, and pain

    The Endocannabinoid System (ECS) is a complex cell-signaling system found in the human body that plays a crucial role in regulating a variety of physiological processes, including mood, appetite, pain sensation, and immune response. It consists of endocannabinoids (naturally occurring compounds), receptors (CB1 and CB2), and enzymes that synthesize and degrade these compounds, helping to maintain homeostasis or balance within the body.

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    Research 30 of 173

    1. The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders Biochemical pharmacology · 2018 · 75 citations
    2. Effect of Hataedock Treatment on Epidermal Structure Maintenance through Intervention in the Endocannabinoid System Evidence-based Complementary and Alternative Medicine · 2020 · 2 citations
    3. The endocannabinoid system and trichotillomania Elsevier eBooks · 2015
    4. Endocannabinoid activation and polycystic ovary syndrome: A systematic review Research journal of pharmacy and technology · 2020 · 5 citations
    5. Age-related changes in endogenous glucocorticoids, gonadal steroids, endocannabinoids and their ratios in plasma and hair from the male C57BL/6 mice General and comparative endocrinology · 2020 · 11 citations
    6. The MHS Hair Restoration Protocol: A Systems-Biology Integration of Nutritional Support, Microbiome Modulation, and Targeted Topical ECS Therapeutics Zenodo (CERN European Organization for Nuclear Research) · 2026
    7. The MHS Hair Restoration Protocol: A Systems-Biology Integration of Nutritional Support, Microbiome Modulation, and Targeted Topical ECS Therapeutics Zenodo (CERN European Organization for Nuclear Research) · 2026
    8. 196 The endocannabinoid tone regulates human sebocyte biology Journal of Investigative Dermatology · 2016
    9. Neuroendocrinology of the hair follicle: principles and clinical perspectives Trends in Molecular Medicine · 2014 · 98 citations
    10. “Sebocytes’ makeup” - Novel mechanisms and concepts in the physiology of the human sebaceous glands 2011 · 58 citations
    11. Targeting Cutaneous Cannabinoid Signaling in Inflammation - A “High”-way to Heal? EBioMedicine · 2017 · 28 citations
    12. Cannabinoids for skin diseases and hair regrowth Journal of Cosmetic Dermatology · 2021 · 20 citations
    13. Human epithelial stem cell survival within their niche requires “tonic” cannabinoid receptor 1‐signalling—Lessons from the hair follicle Experimental Dermatology · 2021 · 14 citations
    14. Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases Cells · 2022 · 3 citations
    15. The possibilities of correction of premature greying of hair and involutive hair changes Medical alphabet · 2024
    16. The relationship of depression, alcohol and marijuana with treatment for LUTS/BPH. PubMed · 2022
    17. A Summary of Pre-Clinical and Clinical Evidence for Cannabinoid Hair Follicle Effects Clinical dermatology open access journal · 2022
    18. Dermatological aspects of synthetic cannabinoid addiction Cutaneous and Ocular Toxicology · 2016 · 14 citations
    19. Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System 2019 · 142 citations
    20. Endocannabinoids limit excessive mast cell maturation and activation in human skin Journal of Allergy and Clinical Immunology · 2012 · 124 citations
    21. Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain Drugs · 2019 · 50 citations
    22. Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations Frontiers in immunology · 2022 · 21 citations
    23. Recent Progress in Prostaglandin F 2a Ethanolamide (Prostamide F2a) Research and Therapeutics 2013 · 1 citations
    24. The role of hemp (Cannabis sativa L.) in cosmeceuticals and personal care: A systematic review International Journal of Applied and Experimental Biology · 2025
    25. Cannabinoids for the Treatment of Hair, Scalp, and Skin Disorders: A Systematic Review Cosmetics · 2023 · 2 citations
    26. LC-APCI+-MS/MS method for the analysis of ten hormones and two endocannabinoids in plasma and hair from the mice with different gut microbiota Journal of pharmaceutical and biomedical analysis · 2020 · 18 citations
    27. Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering Nutrition & Metabolism · 2012 · 119 citations
    28. Chitosan Nanoparticulate System Loaded with Cannabidiol: A Topical Formulation for Potential Alopecia Management Processes · 2025
    29. The skin and obesity International Journal of Dermatology Venereology and Leprosy Sciences · 2025
    30. Skin manifestations of chronic kidney disease Actas Dermo-Sifiliográficas · 2015 · 19 citations