104 citations
,
May 2019 in “F1000Research” This review discusses recent research on male infertility causes and treatments, emphasizing the need for further understanding of idiopathic sperm abnormalities and molecular factors to improve patient outcomes; it reports no new clinical results.
January 2019 in “Indian Journal of Dermatology, Venereology and Leprology” 20 citations
,
March 2021 in “Cancers” This study found that rare germline pathogenic variants in BRCA2, BRCA1, and ATM are associated with increased risk of aggressive prostate cancer.
This review highlights that recent advancements in diagnostics and therapies, including AI-enhanced imaging, biomarker analysis, and novel treatments like low-dose oral minoxidil and JAK inhibitors, are improving the precision and customization of hair loss management.
October 2024 in “Journal of the Endocrine Society” This case study describes a 45-year-old man who developed post-finasteride syndrome with various symptoms after stopping Finasteride, highlighting the condition's rarity and poorly understood pathophysiology.
8 citations
,
July 2021 in “F1000Research” This review discusses the potential of plant-derived phytochemicals as alternatives to 5-alpha-Reductase inhibitors in treating prostate cancer, highlighting possible benefits like reduced side effects, but it reports no new findings.
4 citations
,
April 2020 in “Reports of Practical Oncology & Radiotherapy” This review discusses the role of mental healthcare in managing sexual side effects of prostate cancer radiotherapy and highlights the importance of patient education and psychological support for improved quality of life.
December 2025 in “Cosmetics” This review synthesizes recent molecular and preclinical advances in alopecia areata and androgenetic alopecia, highlighting how interventions targeting specific intracellular signaling pathways and utilizing stem cell technologies can support precision regrowth and structural follicle reconstruction.
August 2025 in “The Journal of Sexual Medicine” This retrospective pharmacovigilance study identified 34 drugs, including finasteride and dutasteride, that may be associated with sexual dysfunction, with a higher risk observed in males aged 31-45.
April 2024 in “Archiv EuroMedica” This study found that platelet-rich plasma therapy increased hair density in androgenetic alopecia and improved hair regrowth in chronic plaque alopecia, with better results when combined with minoxidil rather than finasteride.
March 2023 in “International Journal of Trichology” This study found that a combination of topical 5% minoxidil and 0.25% finasteride was more effective at improving hair density and satisfaction in men with androgenetic alopecia than either treatment alone over 24 weeks.
July 2021 in “Faculty of 1000 Research Ltd” This review discusses the potential of phytochemicals from plants as alternative treatments for prostate cancer, highlighting their possible benefits over current 5-alpha-Reductase inhibitors, but reports no new findings.
June 2021 in “F1000Research” This review explores plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, for their potential use as alternative treatments for prostate cancer, emphasizing their effects on 5-alpha-Reductase enzyme isozymes. It reports no new clinical results.
11 citations
,
April 2025 in “Pharmaceutics” In this review, researchers explore various treatment options for alopecia, focusing on nano-drug delivery systems using plant-based substances, which are potentially effective and less harmful than current treatments, while also highlighting emerging trends such as 3D bioprinting and plant extracts for future therapies.
11 citations
,
May 2022 in “Chinese medicine” This study found that Alpinetin, applied topically in C57BL/6J mice, promoted hair regeneration by activating hair follicle stem cells through Wnt signaling, extending the anagen phase and increasing hair shaft length, with no cytotoxicity observed in keratinocytes and fibroblasts.
8 citations
,
October 2021 in “The international journal of risk and safety in medicine” This paper describes the development of diagnostic criteria for several enduring sexual dysfunction conditions following the use of certain medications, highlighting common sexual and non-sexual symptoms.
7 citations
,
July 2022 in “Pharmaceuticals” This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.
1 citations
,
November 2021 in “British Journal of Clinical Pharmacology” This case report suggests a potential link between the intake of Serenoa repens, commonly known as Saw palmetto, and the onset of erectile dysfunction.
March 2026 in “Preprints.org” This study reviewed evidence for six minimally invasive treatments for androgenetic alopecia, finding consistent support for platelet-rich plasma and topical finasteride, while other options like microneedling and intradermal dutasteride showed promise but need further and standardized research.
November 2024 in “Pharmaceutics” This study found that dutasteride-loaded transfersomes, compared to traditional liposomes, better target hair follicles by releasing the drug in a more controlled manner, as shown in vitro with enhanced follicular targeting (Tf = 0.32 versus 0.15, p < 0.005) using porcine ear skin.
September 2023 in “Cureus” This study reviewed early research on topical finasteride for androgenetic alopecia, finding it appears safe and promising, though further investigation is needed to determine optimal dosing, frequency, and potential applications for other types of alopecia.
October 2021 in “International Journal of Andrology” This paper reports on the controversy surrounding post-finasteride syndrome and questions Merck and the FDA's handling of associated sexual side effects. Despite significant adverse event reports, both entities failed to conduct further studies or enhance patient safety warnings about finasteride's long-term effects.
1 citations
,
March 2021 in “F1000Research” This review discusses plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, as potential alternatives to 5-alpha-reductase inhibitors for prostate cancer treatment, highlighting their promising anti-cancer properties and potentially fewer side effects compared to conventional drugs.
December 2025 in “Phytomedicine Plus” This review summarizes recent advances in alopecia management, focusing on combining synthetic and herbal therapies with innovative drug delivery systems like nanocarriers to enhance effectiveness and reduce side effects, while noting challenges with skin penetration and bioavailability.
October 2025 in “Annals of Medicine and Surgery” This study discusses the potential of topical retinoids, vitamin A derivatives, to improve treatment outcomes for androgenetic alopecia by promoting hair growth through extending the anagen phase and stimulating follicular activity, offering a promising approach when combined with existing therapies.
February 2024 in “ACS Omega” This study found that the topical Shen Bai hair growing decoction may improve androgenetic alopecia in mice by suppressing TNF-α and IL-6 levels, enhancing follicle density, and reducing apoptosis.
January 2024 in “JOJ Dermatology & Cosmetics” This article discusses a trial evaluating patient satisfaction with the TH07 treatment for androgenetic alopecia but reports no clinical results.
April 2023 in “Journal of Cutaneous and Aesthetic Surgery” This review proposes a combination treatment scheme with a rotational approach for managing androgenetic alopecia, drawing on evidence for effectiveness, long-term use convenience, and patient acceptance, but presents no new clinical results.
14 citations
,
May 2016 in “Therapeutic advances in urology” This review examines the use of tadalafil and finasteride as a combined therapy for BPH, suggesting it may effectively reduce treatment-related sexual adverse events and improve symptom relief.
8 citations
,
January 2011 in “Korean Journal of Andrology” This study found that combining 4 mg doxazosin with 0.2 mg tamsulosin improved urinary symptoms with fewer vasodilatory side effects compared to a higher dose of doxazosin in hypertensive males with LUTS.