2 citations
,
April 2024 in “Urology Annals” Taking dutasteride every other day works as well as daily and better preserves sexual function.
November 2013 in “John Wiley & Sons, Ltd eBooks” The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
14 citations
,
August 1997 in “The Journal of Urology” Finasteride can cause enlarged breasts.
77 citations
,
June 2015 in “Nature Reviews Urology” This article reviews the effects of various medications on male fertility, noting that while commonly used drugs can mostly have reversible impacts, conclusive human evidence remains limited.
35 citations
,
May 2020 in “Frontiers in Pharmacology” This review provides a comprehensive overview of the mechanisms, efficacy, and adverse reactions of drugs commonly used for treating benign prostatic hyperplasia but reports no new clinical results.
1 citations
,
July 2023 in “F&S Reviews” This review highlights that various commonly prescribed medications for chronic conditions may impact male fertility by affecting hormone secretion, sperm production, ejaculation, erectile function, and libido, although conclusive evidence is limited to specific drug groups.
October 2010 in “Journal of Men's Health” Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
441 citations
,
May 2008 in “British Journal of Pharmacology” This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.
18 citations
,
March 2019 in “Journal of The European Academy of Dermatology and Venereology” This study found that finasteride use was not associated with sexual dysfunction in men with androgenetic alopecia, consistent with other large survey-based controlled studies.
10 citations
,
October 2018 in “Sexual medicine reviews” This review discusses sexual side effects in men with androgenic alopecia treated with 5-alpha reductase inhibitors and reports no new clinical findings.
10 citations
,
May 2018 in “Neuropharmacology” This study suggests that inhibitors of steroidogenic enzymes may have therapeutic potential for certain behavioral disorders linked to dopaminergic hyperfunction, despite concerns about their endocrine impacts.
January 1995 in “Adolescent and pediatric gynecology” This article reviews genetic and phenotypic aspects of androgen insensitivity syndromes, emphasizing the diversity of mutations that complicates molecular screening and the importance of genotype-phenotype correlations.
127 citations
,
June 2008 in “British Journal of Clinical Pharmacology” This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.
20 citations
,
June 2015 in “Hormone Molecular Biology and Clinical Investigation” This study found that long-term finasteride therapy in men with BPH worsened erectile dysfunction and reduced testosterone levels, while these effects were not observed with tamsulosin.
21 citations
,
July 2018 in “The Journal of Sexual Medicine” This article updates the process of care model for evaluating erectile dysfunction, emphasizing comprehensive evaluation and a combination of pharmacotherapy and counseling tailored to patient dynamics.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.
17 citations
,
December 2018 in “The World Journal of Men s Health” This study concluded that administering dutasteride for more than 8 weeks in rats could lead to irreversible erectile dysfunction, even after stopping the medication.
12 citations
,
September 2017 in “Molecular and Cellular Endocrinology” This review analyzes how androgens impact sexual desire and reproductive behaviors, emphasizing molecular interactions, but provides no new clinical results.
12 citations
,
January 2013 in “Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz” Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.
3 citations
,
January 2019 in “Therapeutic advances in urology” This review concluded that WS PRO 160 I 120 mg, a herbal preparation, may be an effective and safer alternative to standard drugs for treating lower urinary tract symptoms in men with benign prostatic hyperplasia.
In this study, women with stress urinary incontinence who received a platelet-rich plasma injection experienced significant improvement in symptoms without significant adverse reactions.
1 citations
,
February 2022 in “Online journal of biological sciences” This article reviews the congenital disorder aphallia, describing its rarity, clinical characteristics, and the normal hormonal and chromosomal profiles of affected individuals, but does not report new research findings.
14 citations
,
January 2001 in “Primary Care Update for Ob/gyns” This review discusses the challenges in addressing female sexual dysfunction, focusing on the complexities of female sexual response, levels of dysfunction, clinical identification, and existing treatments, but presents no new clinical findings.
June 2024 in “Trends in Urology & Men s Health” This study explores the controversial condition known as post‐finasteride syndrome, observed in some men who experience lasting sexual, neurological, and psychological side effects after stopping finasteride, emphasizing its rarity and the lack of proven treatments.
6 citations
,
July 2021 in “Uro” This review discusses sexual dysfunction as a potential side effect of drugs for Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms and reports no new clinical results; it emphasizes the need for methodologically robust studies.
10 citations
,
December 2014 in “PubMed” This review examines reports of prolonged sexual dysfunction and depression associated with finasteride for male pattern hair loss, concluding that significant biases exist and further rigorous trials are needed to assess risks.
6 citations
,
June 2022 in “Journal of Clinical Medicine” This study found that for men with moderate-to-severe LUTS/BPH, 6 months of treatment with tamsulosin plus the hexanic extract of S. repens was as effective as tamsulosin plus a 5-alpha-reductase inhibitor but had better tolerability.
1 citations
,
January 2022 in “Journal of Biosciences and Medicines” This review discusses the roles of androgens and androgen receptor in skin diseases like acne and hirsutism, and highlights the promise of antiandrogen drugs, reporting no new clinical findings.
This review highlights that recent advancements in diagnostics and therapies, including AI-enhanced imaging, biomarker analysis, and novel treatments like low-dose oral minoxidil and JAK inhibitors, are improving the precision and customization of hair loss management.
April 2021 in “IntechOpen eBooks” This article discusses the need to investigate long-term effects of androgen manipulations independently of current levels, referencing Post-finasteride Syndrome as a relevant clinical example, and reports no new results.