6 citations
,
July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study observed that HAP stem cells from the whiskers of young mice near the ear differentiated into heart-muscle cells more efficiently than those from older mice or other whisker locations.
6 citations
,
July 2015 in “Journal of Investigative Dermatology” Chicken feather gene mutation helps understand human hair disorders.
5 citations
,
May 2017 in “International Journal of Research in Dermatology” This study found that early onset of androgenetic alopecia in men is commonly associated with a history of alcohol consumption and paternal inheritance, while smoking was not linked to onset age.
4 citations
,
December 2021 in “Pharmacological Reports” This study found that metformin's metabolic benefits, such as reducing fat content and improving insulin sensitivity, were less pronounced in men with early-onset androgenic alopecia compared to those with normal hair growth, possibly due to differences in systemic inflammation and vitamin D status.
3 citations
,
February 2022 in “Journal of Dermatological Science” This study identified clinical features and genetic variants associated with early onset female pattern hair loss, highlighting decreased hair shaft density and specific SNPs related to androgenic features.
3 citations
,
May 2021 in “Molecules” This study found that men with early-onset androgenetic alopecia may experience less benefit from rosuvastatin treatment in terms of improving cardiometabolic risk factors compared to men with normal hair growth.
3 citations
,
April 2016 in “International Journal of Dermatology” This article presents a clinicopathologic challenge involving early leonine facies with alopecia in a young man and reports no new clinical results.
2 citations
,
March 2023 in “Journal of Nepal Medical Association” This study found that 40.42% of undergraduate medical students aged under 25 had early canities, with grade I being the most common.
2 citations
,
January 2022 in “Italian journal of dermatology and venereology” This study found that 19.2% of male university students had early-onset androgenetic alopecia, with family history, unhealthy diet, and certain lifestyle factors linked to its increased risk.
2 citations
,
July 2020 in “Behavioural Brain Research” This study found that neonatal administration of finasteride affected adult learning and memory in rats, enhancing object recognition but impairing aversive learning, with no effect on anxiety-like behavior.
2 citations
,
December 2019 in “Neurobiology of Stress” This review discusses the potential link between early postnatal allopregnanolone levels and vulnerability to drug abuse in adulthood, noting a need for more in-depth studies to confirm this relationship.
2 citations
,
January 2019 in “Skin appendage disorders” This article reports a case of frontal fibrosing alopecia in its early inflammatory stage that responded positively to intralesional steroid treatment.
2 citations
,
June 2018 in “Physiology & behavior” The study found that ondansetron decreased alcohol consumption only in adult rats that experienced altered neuroactive steroid levels from early post-natal finasteride exposure, suggesting increased 5HT3 receptor sensitivity in these rats.
1 citations
,
December 2025 in “Scientific Reports” In this study, researchers developed a predictive model for the onset of alopecia areata by analyzing six datasets to identify key feature genes and employing various machine learning algorithms, ultimately finding the XGBoost model most effective for clinical application.
1 citations
,
December 2023 in “Experimental Dermatology” This study reported that 57.4% of children under 10 with early-onset alopecia areata experienced over 50% hair regrowth after treatment with topical corticosteroids, noting that those under 4 showed significantly better responses, although personal atopic history was the only differing prognostic factor.
1 citations
,
September 2023 In this study, autologous micrografting technology using auricular cartilage was reported to be safe and effective for improving knee function and reducing symptoms in patients with early-stage knee osteoarthritis over six months, but larger studies are needed to confirm these results.
1 citations
,
January 2023 in “Pediatric Dermatology” This case study of a neonate with ichthyosis and ILVASC demonstrates how an interdisciplinary approach facilitated a timely genetic diagnosis and management of complications.
1 citations
,
January 2020 in “International Journal of Trichology” This study found that patients with early onset androgenetic alopecia had significantly higher levels of the biomarker YKL-40, suggesting a link to both the condition's pathogenesis and related metabolic syndrome.
1 citations
,
January 2018 in “Turkiye Klinikleri Journal of Dermatology” This study found that early onset androgenetic alopecia in males is associated with a higher frequency of metabolic syndrome, particularly dyslipidemia, compared to controls.
1 citations
,
January 2015 in “Journal of Dermatology and Venereology” This study concluded that androgenetic alopecia may predict ischemic heart disease, and recommended that patients with AGA be screened for coronary artery disease.
1 citations
,
June 2013 in “Annals of the Rheumatic Diseases” This study observed that while all DMARD regimens had similar safety profiles, the leflunomide group experienced the most serious side effects leading to therapy discontinuation.
1 citations
,
May 2011 in “Hair transplant forum international” This article discusses the potential of platelet rich plasma injections for treating hair loss but reports no new clinical results, emphasizing the need for further research.
1 citations
,
October 1996 in “PubMed” This study found that common side effects leading to premature removal of the Norplant contraceptive implant included uterine bleeding, amenorrhea, and headaches, suggesting the need for improved pre-insertion counseling and screening.
July 2026 in “International Journal of Advanced Research in Science Communication and Technology” In this study, the BaldGraphFormer framework, integrating visual and clinical data, outperformed unimodal baselines in early-stage androgenetic alopecia detection, achieving an F1-score of 97.62% and macro-average AUC of 0.992, suggesting its potential to support dermatological decision-making and early intervention.
July 2026 in “Journal of the American Academy of Dermatology” Early hair loss may signal metabolic issues but doesn't predict diabetes.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case report concludes that early-onset alopecia areata does not independently predict poorer long-term outcomes, with prognosis more strongly influenced by baseline severity and treatment response.
This case study describes a 34-year-old male developing painful inflammatory scalp nodules post-scalp microinfusion of medication. The findings suggest that repeated microtrauma or bacterial colonization might trigger dissecting cellulitis in susceptible individuals, with exogenous testosterone as a potential modifier, not a direct cause.
May 2026 in “Frontiers in Medicine” In this study, a keratolytic shampoo with 2% salicylic acid was found to effectively reduce scab severity in male patients after hair transplantation without causing adverse symptoms, leading to high patient satisfaction and no recorded adverse events.
May 2026 in “Journal of the American Academy of Dermatology” Early hair loss might indicate diabetes and heart risks, especially in those under 45.
March 2026 in “Journal of the American Academy of Dermatology” Early hair loss may indicate a higher risk of diabetes in young and middle-aged adults.