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January 2018 in “Turkiye Klinikleri Journal of Dermatology” This study found that early onset androgenetic alopecia in males is associated with a higher frequency of metabolic syndrome, particularly dyslipidemia, compared to controls.
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January 2015 in “Journal of Dermatology and Venereology” This study concluded that androgenetic alopecia may predict ischemic heart disease, and recommended that patients with AGA be screened for coronary artery disease.
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June 2013 in “Annals of the Rheumatic Diseases” This study observed that while all DMARD regimens had similar safety profiles, the leflunomide group experienced the most serious side effects leading to therapy discontinuation.
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May 2011 in “Hair transplant forum international” This article discusses the potential of platelet rich plasma injections for treating hair loss but reports no new clinical results, emphasizing the need for further research.
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January 2010 in “STARS (University of Central Florida)” This study found that men receiving negative appearance-related commentary are more likely to experience negative psychological outcomes, while positive feedback tends to lead to better outcomes despite encouraging appearance-change behaviors.
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October 1996 in “PubMed” This study found that common side effects leading to premature removal of the Norplant contraceptive implant included uterine bleeding, amenorrhea, and headaches, suggesting the need for improved pre-insertion counseling and screening.
August 2024 in “Archives of Dermatological Research” This study found that individuals with early-onset androgenetic alopecia showed significant differences in metabolic parameters compared to those with normal-onset alopecia, suggesting a potential link between androgenetic alopecia and metabolic syndrome. However, the nature of this relationship remains uncertain.
June 2024 in “Research Square (Research Square)” In this cross-sectional study, researchers observed that individuals with early-onset androgenetic alopecia showed significant differences in hair growth parameters and metabolic factors compared to those with normal-onset AGA, suggesting a potential association with metabolic syndrome, though more research is needed to clarify this relationship.
June 2012 in “Springer eBooks” Eating disorders can cause various hair problems, and while hair loss in these disorders is linked to metabolic syndrome, treatment focuses on specific medications and lifestyle changes for the syndrome.
July 2026 in “International Journal of Advanced Research in Science Communication and Technology” In this study, the BaldGraphFormer framework, integrating visual and clinical data, outperformed unimodal baselines in early-stage androgenetic alopecia detection, achieving an F1-score of 97.62% and macro-average AUC of 0.992, suggesting its potential to support dermatological decision-making and early intervention.
July 2026 in “Journal of the American Academy of Dermatology” Early hair loss may signal metabolic issues but doesn't predict diabetes.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case report concludes that early-onset alopecia areata does not independently predict poorer long-term outcomes, with prognosis more strongly influenced by baseline severity and treatment response.
This case study describes a 34-year-old male developing painful inflammatory scalp nodules post-scalp microinfusion of medication. The findings suggest that repeated microtrauma or bacterial colonization might trigger dissecting cellulitis in susceptible individuals, with exogenous testosterone as a potential modifier, not a direct cause.
May 2026 in “Frontiers in Medicine” In this study, a keratolytic shampoo with 2% salicylic acid was found to effectively reduce scab severity in male patients after hair transplantation without causing adverse symptoms, leading to high patient satisfaction and no recorded adverse events.
May 2026 in “Journal of the American Academy of Dermatology” Early hair loss might indicate diabetes and heart risks, especially in those under 45.
In this study, baseline neutrophil-to-lymphocyte ratio (NLR) was associated with predicting early trichoscopic response in patients undergoing PRP-based treatment for non-scarring alopecia.
April 2026 in “Aesthetic Plastic Surgery” This study reported that a standardized hair transplantation procedure significantly improved both patient and surgeon satisfaction with aesthetic results for East Asian women with non-ideal facial proportions, achieving a natural-looking hairline without significant complications.
March 2026 in “Journal of the American Academy of Dermatology” Early hair loss may indicate a higher risk of diabetes in young and middle-aged adults.
March 2026 in “Journal of Surgical Case Reports” In this case report, a 46-year-old man developed scalp necrosis with infection following FUE hair transplantation, possibly due to factors like smoking, long surgery duration, dense grafting, and secondary infection. Early recognition and treatment prevented further tissue loss, but the patient had residual scarring.
March 2026 in “Journal of Investigative Dermatology” This study identified CCCA in 10 children of African descent, highlighting the occurrence of this scarring alopecia in patients under 18 and the importance of early diagnosis for better outcomes.
February 2026 in “Mendeley Data” This study, accepted for publication in the Journal of the American Academy of Dermatology, discusses the potential link between early androgenetic alopecia, diabetes mellitus, and cardiovascular disease risks, exploring its role as an indicator in a cross-sectional analysis.
February 2026 in “Mendeley Data” This study observed that early androgenetic alopecia could potentially serve as an indicator for diabetes mellitus and might be linked to cardiovascular risks, as reported in a cross-sectional analysis.
December 2025 in “Journal of Pharmacy And Bioallied Sciences” In this study, trichoscopy was found to enhance the early assessment of minoxidil therapy in males with pattern hair loss, leading to improved satisfaction and treatment compliance by revealing positive changes visible within one month.
July 2025 in “Harvard Dataverse” A deep learning model accurately detects early hair loss signs using scalp images.
July 2025 in “Journal of Advanced Nursing” This study observed that first-time mothers reported a gradual decrease in postpartum symptoms from an average of 7 at one month to 5.3 at three months, with pervasive issues like lack of energy and irritability, especially among older mothers.
July 2025 in “Journal of Cutaneous Pathology” In this case report, a newborn with Conradi-Hünermann-Happle syndrome was diagnosed through early skin biopsy, which revealed unique histopathological features, including dystrophic calcifications, confirming a pathogenic variant in the EBP gene.
July 2025 in “Reproductive Biology and Endocrinology” This study found that early postnatal androgen activity affects the long-term expression of hormone receptors differently in female Wistar rats, influencing neural system programming during development.
May 2025 in “Neuropharmacology” This study in neonatal rats found that inhibiting neurosteroid synthesis with finasteride unexpectedly reduced the severity and duration of neonatal seizures following birth asphyxia, maintained cognitive functions, but increased anxiety-like behaviors, highlighting a complex role of neurosteroids in hypoxic-ischemic encephalopathy outcomes.
April 2025 in “International Journal For Multidisciplinary Research” This case report details the investigation and management of a 3-year-old girl with precocious pseudopuberty due to a Sertoli-Leydig cell tumor, highlighting the importance of early recognition and accurate diagnosis for effective treatment and prognosis.
April 2025 in “Brazilian Journal of Hair Health” This article suggests that cultural and environmental influences, such as exposure to sexualized content, stress, poor sleep, and unhealthy diets, may accelerate androgenetic alopecia onset by affecting hormonal systems, gene expression, and hair follicle health, despite its genetic basis.