10 citations
,
January 2019 in “International Immunology” This review discusses the interactions between immune cells and the skin epithelium and their impact on maintaining barrier function, emphasizing the potential to enhance epithelial barrier function in inflammatory diseases.
10 citations
,
January 2019 in “Indian Journal of Dermatology” This study found that male patients with early-onset androgenetic alopecia were associated with metabolic syndrome, but not insulin resistance, compared to age-matched controls.
8 citations
,
February 2020 in “Aesthetic Surgery Journal” This study found that early male hair loss treatment with Puregraft fat and low-dose adipose-derived regenerative cells increased terminal hair counts at 24 weeks compared to a saline control, indicating promise for androgenetic alopecia treatment.
8 citations
,
August 2013 in “PubMed” In this study, early onset androgenic alopecia in Thai men was associated with metabolic syndrome, suggesting that early detection of metabolic syndrome in these individuals may help prevent cardiovascular diseases.
7 citations
,
December 2021 in “Journal of The American Academy of Dermatology” This article discusses early-onset telogen effluvium following COVID-19 infection and reports no new results, encouraging further exploration into its pathogenesis and differences compared to other acute forms.
7 citations
,
November 2006 in “Pediatric Dermatology” This article describes the first reported case of alopecia in a neonate with congenital syphilis.
7 citations
,
June 2001 in “PubMed” This study details the histological structure of the white domesticated pig's ear skin and discusses its relevance as a model for human dermatological research.
6 citations
,
March 2020 in “Journal of International Medical Research” This study reported that early-onset androgenetic alopecia primarily affects Chinese males aged 21–30, with a high likelihood of paternal inheritance.
6 citations
,
July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study observed that HAP stem cells from the whiskers of young mice near the ear differentiated into heart-muscle cells more efficiently than those from older mice or other whisker locations.
6 citations
,
July 2015 in “Journal of Investigative Dermatology” Chicken feather gene mutation helps understand human hair disorders.
5 citations
,
May 2017 in “International Journal of Research in Dermatology” This study found that early onset of androgenetic alopecia in men is commonly associated with a history of alcohol consumption and paternal inheritance, while smoking was not linked to onset age.
4 citations
,
November 2017 in “Cancer Causes & Control” This study found that men with androgenetic alopecia at age 20 years may have a higher risk of developing aggressive prostate cancer, particularly advanced stage disease.
4 citations
,
September 2023 in “Nutrients” This review highlights the complex relationship between eating disorders and diabetes, indicating that individuals with diabetes may be at increased risk for eating disorders due to dietary and management demands, which can in turn affect blood sugar control.
4 citations
,
December 2021 in “Pharmacological Reports” This study found that metformin's metabolic benefits, such as reducing fat content and improving insulin sensitivity, were less pronounced in men with early-onset androgenic alopecia compared to those with normal hair growth, possibly due to differences in systemic inflammation and vitamin D status.
3 citations
,
February 2022 in “Journal of Dermatological Science” This study identified clinical features and genetic variants associated with early onset female pattern hair loss, highlighting decreased hair shaft density and specific SNPs related to androgenic features.
3 citations
,
May 2021 in “Molecules” This study found that men with early-onset androgenetic alopecia may experience less benefit from rosuvastatin treatment in terms of improving cardiometabolic risk factors compared to men with normal hair growth.
3 citations
,
April 2016 in “International Journal of Dermatology” This article presents a clinicopathologic challenge involving early leonine facies with alopecia in a young man and reports no new clinical results.
3 citations
,
September 2006 in “Hair transplant forum international” This article discusses the use of forceps in hair restoration surgery and does not report any new clinical results.
2 citations
,
January 2025 in “Development” In this study, researchers explored ear pinna development in two rodent species and identified that BMP5 plays a crucial role in chondroblast proliferation but not in their initial specification, with implications for understanding tissue differentiation and potential impacts on reconstructive surgery.
2 citations
,
March 2023 in “Journal of Nepal Medical Association” This study found that 40.42% of undergraduate medical students aged under 25 had early canities, with grade I being the most common.
2 citations
,
January 2022 in “Italian journal of dermatology and venereology” This study found that 19.2% of male university students had early-onset androgenetic alopecia, with family history, unhealthy diet, and certain lifestyle factors linked to its increased risk.
2 citations
,
July 2020 in “Behavioural Brain Research” This study found that neonatal administration of finasteride affected adult learning and memory in rats, enhancing object recognition but impairing aversive learning, with no effect on anxiety-like behavior.
2 citations
,
December 2019 in “Neurobiology of Stress” This review discusses the potential link between early postnatal allopregnanolone levels and vulnerability to drug abuse in adulthood, noting a need for more in-depth studies to confirm this relationship.
2 citations
,
January 2019 in “Skin appendage disorders” This article reports a case of frontal fibrosing alopecia in its early inflammatory stage that responded positively to intralesional steroid treatment.
2 citations
,
June 2018 in “Physiology & behavior” The study found that ondansetron decreased alcohol consumption only in adult rats that experienced altered neuroactive steroid levels from early post-natal finasteride exposure, suggesting increased 5HT3 receptor sensitivity in these rats.
1 citations
,
December 2025 in “Scientific Reports” In this study, researchers developed a predictive model for the onset of alopecia areata by analyzing six datasets to identify key feature genes and employing various machine learning algorithms, ultimately finding the XGBoost model most effective for clinical application.
1 citations
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December 2023 in “Experimental Dermatology” This study reported that 57.4% of children under 10 with early-onset alopecia areata experienced over 50% hair regrowth after treatment with topical corticosteroids, noting that those under 4 showed significantly better responses, although personal atopic history was the only differing prognostic factor.
1 citations
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September 2023 In this study, autologous micrografting technology using auricular cartilage was reported to be safe and effective for improving knee function and reducing symptoms in patients with early-stage knee osteoarthritis over six months, but larger studies are needed to confirm these results.
1 citations
,
January 2023 in “Pediatric Dermatology” This case study of a neonate with ichthyosis and ILVASC demonstrates how an interdisciplinary approach facilitated a timely genetic diagnosis and management of complications.
1 citations
,
January 2020 in “International Journal of Trichology” This study found that patients with early onset androgenetic alopecia had significantly higher levels of the biomarker YKL-40, suggesting a link to both the condition's pathogenesis and related metabolic syndrome.