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In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect hair cells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.

This review highlights how advanced nanocarrier and microneedle-based transdermal drug delivery strategies can potentially improve the treatment of skin diseases by enhancing site-specific drug delivery, increasing skin penetration, and reducing systemic toxicity compared to conventional methods.

This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.

This review highlights phytochemicals, particularly flavonoids and phenolics, as potential supportive treatments for SARS-CoV-2 by interfering with viral proteins and providing anti-inflammatory effects; it suggests a foundation for future therapeutic and vaccine development efforts.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

This review discusses the potential of metal organic frameworks for drug delivery in wound treatment, highlighting their unique properties and recent research advancements, but reports no new clinical results.

This review discusses the potential anticancer effects of medicinal plants, highlighting their diverse phytoconstituents and mechanisms, and considers both their future prospects and limitations in cancer treatment.

This article discusses the potential benefits of GcMAF and oral MAF, developed by "Saisei Mirai", for cancer and other conditions, but reports no new clinical results.

In this study, the ethyl acetate extract of Semecarpus anacardium Linn leaves was reported to induce cytotoxicity in cancer cells, cause cell cycle arrest, and suppress tumor growth in mice.

This review highlights cepharanthine as a promising candidate for COVID-19 treatment due to its antiviral activity against SARS-CoV-2 and favorable pharmacokinetic and safety profile, but reports no new clinical results.

This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.

Effective vaccines and treatments are crucial for long-term COVID-19 control.

This review discusses the integration of biodegradable biomaterials with drugs and stem cells for diabetic wound repair, but reports no new clinical results and highlights the need for further translation to clinical practice.

This review provides an overview of natural product-derived small molecule modulators of the Wnt signaling pathway, exploring their potential as therapeutic agents for tissue regeneration and cancer treatment.

This review discusses advances in drug delivery systems to enhance oleanolic acid's bioavailability and therapeutic potential but reports no new clinical results.

This review outlines the urgent need for effective therapeutic interventions against coronaviruses, as current vaccines are challenged by virus mutations, and emphasizes developing safe, affordable, and broad-spectrum antivirals for both human and porcine coronaviruses.

This review discusses the patterns and regulatory mechanisms of keratin expression in various biological conditions and reports no new experimental results.

This study highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research, emphasizing their roles in controlled drug delivery, tissue regeneration, and treatment of various conditions, such as cardiac issues, joint diseases, and bone regeneration.

This narrative review suggests that nutraceutical insulin-sensitizing agents like myo-inositol, alpha-lipoic acid, and vitamins may improve glycemic control and reduce inflammation in insulin resistance-related skin disorders; however, more robust long-term trials are needed to confirm these findings and establish treatment regimens.

This study highlights the clinical potential of microneedles as an innovative transdermal drug delivery system for treating various skin diseases with minimal pain and high patient compliance.

This study found that transgenic mice with expression of HPV16 E6/E7 oncogenes showed improved ear tissue regeneration, including hair follicles and cartilage, without tumor formation.

This study found that transgenic mice expressing HPV E6/E7 in the outer root sheath experience continuous hair follicle cycling due to delayed catagen entrance and insensitivity to telogen resting signals.

This study found that the E6 gene, but not E7, was responsible for HPV8-induced expansion of keratinocyte stem cells in hair follicle junctional zones in mice.

This study found that HPV8-induced actinic keratoses may mechanistically involve Lrig1+ hair follicle keratinocyte stem cells, with the E6 gene promoting downstream STAT3 activity in a mouse model.

This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.

This study reported that immortalizing human dermal papilla cells using HPV16 E6/E7 oncogenes increased their proliferation and maintained their hair follicle formation capability, potentially facilitating in vitro hair growth and regeneration research.

This study observed that human dental pulp stem cells can differentiate into adipocytes and osteocytes, but their potential for neural differentiation remains uncertain due to similar responses seen in undifferentiated cells.

This study found that dermatoscopy can quickly and non-invasively detect facial vellus hair involvement in patients with alopecia frontal fibrosante, occurring frequently and associated with specific facial lesions.

In this integrative review, researchers assessed the efficacy of oral minoxidil for treating alopecia, finding that it appears effective, especially for female androgenetic alopecia, though evidence quality is very low and side effects limit its use compared to topical forms.