24 citations
,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
23 citations
,
September 2021 in “Frontiers in Medicine” This report describes a rare case of pityriasis rosea-like eruption in a 52-year-old Thai woman following Oxford/AstraZeneca COVID-19 vaccination, emphasizing the condition does not preclude further vaccinations.
23 citations
,
June 2015 in “Oncology Letters” This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.
22 citations
,
June 2018 in “Journal of Neuroinflammation” This study found that procyanidins effectively alleviate neuropathic pain in mice by significantly inhibiting MMP-9/2 activity.
20 citations
,
March 2013 in “Journal of Lipid Research” This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.
19 citations
,
December 2015 in “Journal of Materials Chemistry B” This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.
17 citations
,
December 2019 in “Stem Cell Research & Therapy” This study found that their system effectively supports the rapid formation of human hair follicle organoids, providing a platform for studying hair regeneration and drug screening.
16 citations
,
May 2019 in “Hormone and Metabolic Research” This systematic review found insufficient evidence to support protective effects of selenium on polycystic ovary syndrome complications, despite some studies suggesting it may reduce insulin resistance and dyslipidemia.
15 citations
,
May 2023 in “npj Regenerative Medicine” This study found that mammary resident macrophages play a key role in mammary tissue development by influencing cell division and maintaining mammary stem cell activity through the TNF-α-Cdk1/Cyclin B1 signaling pathway, highlighting their importance in the mammary stem cell niche.
15 citations
,
December 2016 in “Obstetrics & Gynecology” This review discusses the effects of pregnancy on melanocytic nevi and reports no new clinical results; it suggests that changing nevi during pregnancy should be evaluated similarly to those in nonpregnant patients.
14 citations
,
April 2021 in “Biology” This study found that ethanol extract of Tubtim Chumphae rice bran downregulates SRD5A gene expression, similarly to finasteride, suggesting potential use as an anti-hair loss product.
13 citations
,
September 2021 in “Communications Biology” This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.
13 citations
,
February 2006 in “Analytical Biochemistry” This study reported a simple and validated gas chromatography method to accurately measure finasteride in tablets, showing equivalency to the official method with no significant differences.
11 citations
,
October 2019 in “Cancers” This study found that spironolactone enhanced the effectiveness of non-DNA-damaging cancer drugs gemcitabine and osimertinib in cancer cell lines and a mouse xenograft model, likely by suppressing the anti-apoptotic protein survivin.
10 citations
,
March 2019 in “Human Genetics” This study identified a genetic variant in the SGK3 gene related to hairlessness in Scottish Deerhounds, suggesting a similar role for androgen-independent hair loss in humans.
10 citations
,
November 2017 in “Advances in Dermatology and Allergology” This study found that scalp involvement in pemphigus is linked to greater disease severity and longer times to achieve both clinical and serological remission, suggesting it may require more aggressive treatment.
8 citations
,
April 2024 in “Cureus” This review compares the CO2 and Er:YAG laser treatments for acne scars, noting that while CO2 lasers offer deeper tissue penetration for severe scars, Er:YAG lasers pose a lower risk of post-inflammatory hyperpigmentation, and recommends personalizing treatments and considering combination therapies.
8 citations
,
April 2020 in “Journal of Ethnopharmacology” This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.
7 citations
,
January 2021 in “Biology” This study documented a variety of skin lesions in COVID-19 patients, indicating that skin rashes might be an early or sole symptom of the disease.
7 citations
,
June 2021 in “Trends in Food Science and Technology” This commentary reviews potential dietary and mineral influences on androgenetic alopecia and suggests considering a diet low in cholesterol and glycaemic index with improved glucose control and magnesium fortification, without new clinical results.
7 citations
,
July 2020 in “Pigment cell & melanoma research” In this study, RT1640 was found to promote hair pigment system regeneration and expand melanocyte stem cell pools in a mouse model, suggesting potential applications for aging-related hair disorders.
7 citations
,
December 2017 in “Anais da Academia Brasileira de Ciências” This study found that 6-Gingerol significantly suppressed hair growth in mice by reducing hair follicle number and length, potentially through increased expression of MMP2 and MMP9.
7 citations
,
March 2017 in “Journal of dermatology” This review outlines the clinical and histopathological features that aid in classifying tumors arising from the folliculosebaceous apparatus and reports no new research results.
6 citations
,
August 2017 in “Physiological Research” This study suggests that setipiprant's inhibitory effect on aldose reductase may contribute to its anti-inflammatory properties, adding a possible mechanism beyond its known action on the prostaglandin D2 receptor.
5 citations
,
August 2020 in “Stem Cell Research & Therapy” This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.
5 citations
,
March 2025 in “World Journal of Urology” This study concluded that while remote interventions using digital health technology can enhance health-related outcomes, medication adherence, and economic status in kidney transplant recipients, their effect on tacrolimus concentration is not clearly understood.
5 citations
,
January 2024 in “The International Journal of Developmental Biology” This article reviews the diversity of lymphatic endothelial cells, related gene targeting tools, and protocols in mouse models but presents no new experimental findings.
5 citations
,
October 2015 in “The American journal of pathology” This study found that a spontaneous deletion in the Dsg3 gene of mice leads to hypomorphic desmoglein 3 expression, resulting in severe immunodeficiency, cyclic hair loss, and wasting disease, without causing the blistering typical of pemphigus vulgaris.
4 citations
,
March 2020 in “Cutaneous and ocular toxicology” In this double-blind, randomized controlled study, researchers found that Wen by Chaz Dean Sweet Almond Mint Cleansing Conditioner was similarly tolerated compared to three other hair cleansing conditioners and was significantly better tolerated than salicylic acid shampoo or baby shampoo in terms of skin reactions.
4 citations
,
January 2026 in “Cell Discovery” This study introduced the concept of spatiotemporal clocks to understand how different phases of mammalian wound healing are coordinated, with a focus on the spatial domains and oscillatory molecular signals involved, while highlighting the potential for regenerative therapeutic strategies.