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    Glossary Dystrophic Hairs

    hairs damaged or weakened by underlying scalp conditions

    Dystrophic hairs are hairs that have been damaged or weakened, often due to underlying conditions such as alopecia areata or other scalp disorders. These hairs typically appear thin, fragile, and may break easily, reflecting a disruption in the normal hair growth cycle. For professionals, the presence of dystrophic hairs can be a diagnostic clue indicating an active disease process affecting the hair follicles.

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    1. Patients with profuse hair shedding may reveal anagen hair dystrophy: a diagnostic clue of alopecia areata incognita Journal of the European Academy of Dermatology and Venereology · 2010 · 31 citations
    2. Modulation of Chemotherapy-Induced Human Hair Follicle Damage by 17-β Estradiol and Prednisolone: Potential Stimulators of Normal Hair Regrowth by “Dystrophic Catagen” Promotion? Journal of Investigative Dermatology · 2008 · 18 citations
    3. 259 Scalp hair follicle dermal sheath fibroblasts express genes associated with promotion of skin integrity/wound healing and prevention of autoimmune responses in Recessive Dystrophic Epidermolysis Bullosa Journal of Investigative Dermatology · 2024
    4. A childhood case of trichotillomania associated with body dysmorphic disorder and stigmatization due to outstanding red hair International Journal of Trichology · 2013 · 1 citations
    5. Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression Veterinary Pathology · 1997 · 69 citations
    6. Hair follicle dystrophy in a litter of domestic cats resembling lanceolate hair mutant mice Veterinary dermatology · 2021 · 3 citations
    7. Hair Loss Dysmorphic Disorder – a Frequently Encountered and Often Neglected Disorder Dermatology + psychosomatics · 2002 · 1 citations
    8. Hair-Related Dysmorphic Disorder in a Patient with Bipolar Disorder Brazilian Journal of Hair Health · 2024
    9. Evaluation of body dysmorphic disorder in hair loss patients and benefit after hair restoration Hair transplant forum international · 2012
    10. Frequency of body dysmorphic disorder among patients with complaints of hair loss International Journal of Dermatology · 2015 · 13 citations
    11. Selenium in the supplement as the probable cause of hair loss and nail dystrophy Journal of cosmetic dermatology (Print) · 2023 · 1 citations
    12. Perfectionism and Body Dysmorphic Disorder Symptoms among Men Seeking and Not Seeking Hair Transplant Qlantic Journal of Social Sciences and Humanities · 2024
    13. Pretreatment of epidermal growth factor promotes primary hair recovery via the dystrophic anagen pathway after chemotherapy‐induced alopecia Experimental Dermatology · 2013 · 25 citations
    14. Independent DSG4 frameshift variants in cats with hair shaft dystrophy Molecular genetics and genomics · 2021
    15. 17‐beta estradiol and prednisolone as potential stimulators of hair re‐growth in chemotherapy‐induced human hair follicle damage via ‘dystrophic catagen’ promotion? Experimental Dermatology · 2008
    16. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation Nutrients · 2018 · 19 citations
    17. Overcoming genetic drivers in alopecia areata: hair regrowth in a patient with <i>AIRE</i> gene mutation (autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy, APECED syndrome) treated with ruxolitinib Clinical and Experimental Dermatology · 2026
    18. Transplantation of autologous single hair units heals chronic wounds in autosomal recessive dystrophic epidermolysis bullosa: A proof-of-concept study Journal of Tissue Viability · 2020 · 7 citations
    19. Topical Estrogen Accelerates Hair Regrowth in Mice After Chemotherapy-Induced Alopecia by Favoring the Dystrophic Catagen Response Pathway to Damage Journal of Investigative Dermatology · 2004 · 76 citations
    20. 051 γδ T cells as novel players in alopecia areata pathobiology: Vδ1 + T lymphocytes may recognize “stressed” hair follicle keratinocytes, leading to IFNγ-dependent hair follicle dystrophy and immune privilege collapse Journal of Investigative Dermatology · 2016 · 1 citations
    21. 441 Anti-melanoma gene signature in dermal sheath fibroblasts from scalp hair follicles in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Journal of Investigative Dermatology · 2024
    22. Corkscrew Hair: A New Dermoscopic Sign for Diagnosis of Tinea Capitis in Black Children Archives of Dermatology · 2011 · 108 citations
    23. Dermoscopy in hair disorders Menoufia Medical Journal · 2014 · 12 citations
    24. Hair loss in cancer chemotherapeutic patients. PubMed · 2007 · 10 citations
    25. Hair and Scalp Disorders 2020 · 8 citations
    26. The Near-Naked Hairless (Hr) Mutation Disrupts Hair Formation but Is Not Due to a Mutation in the Hairless Coding Region 2007 · 8 citations
    27. Histologic and Cell Kinetic Studies of Hair Loss and Subsequent Recovery Process of Human Scalp Hair Follicles Grafted onto Severe Combined Immunodeficient Mice Journal of Investigative Dermatology · 2000 · 31 citations
    28. A comparative study of histopathologic features in alopecia areata and pattern hair loss Journal of Cutaneous Pathology · 2023
    29. Chemotherapy Targets the Hair-Follicle Vascular Network but Not the Stem Cells Journal of Investigative Dermatology · 2006 · 45 citations
    30. The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle Journal of Investigative Dermatology · 2016 · 18 citations