18 citations
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April 2013 in “PLOS ONE” This study found that in a mouse model, alopecia areata was associated with changes in heart structure, biochemistry, and gene expression linked to cardiac hypertrophy after ACTH exposure.
January 2025 in “Universidad de Córdoba Insitutional Repository (Universidad de Córdoba)” In this study, researchers observed that individuals with alopecia areata exhibited significant changes in scalp microbiota diversity and composition, which were linked to disease severity and inflammation markers, though it remains unclear if these microbial shifts are a cause or a result of hair loss.
19 citations
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October 2011 in “Clinics in Dermatology” This review discusses the cutaneous side effects of chemotherapy, noting that they frequently involve changes to skin, hair, and nails, and reports no new results.
6 citations
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May 2013 in “PloS one” This study found that the Foxn1(-/-) nude phenotype significantly influences epithelial progeny in skin, with notable changes in stem cell niches not achievable in other models.
August 2022 in “Case reports in medicine” This case report describes a 19-year-old female with systemic lupus erythematosus who exhibited eyelash trichomegaly, a rare disorder involving changes in eyelash characteristics, alongside diffuse alopecia.
214 citations
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March 1993 in “Archives of Dermatology” This article proposes five different mechanisms for telogen effluvium, supported by clinical findings, based on changes in different phases of the hair cycle.
4 citations
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May 2022 in “Journal of Nepal Medical Association” This case report describes a 40-year-old woman with Cronkhite-Canada Syndrome whose symptoms, including gastrointestinal issues and skin changes, improved significantly with corticosteroids, co-infection treatment, and nutritional counseling.
August 2016 in “Journal of Dermatology” This research successfully established a novel mouse model for anagen effluvium using BrdU treatment, which induced hair loss and pathological changes mimicking human symptoms.
April 1963 in “Archives of Dermatology” This case study details the progression of a woman's skin conditions, initially diagnosed as acanthosis nigricans and later as mycosis fungoides, with changes in lesion characteristics and distribution over time.
76 citations
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March 2005 in “Journal of Molecular Medicine” This study found that premature hair loss due to stress does not occur in NK-1 receptor knockout or mast cell deficient mice, suggesting a key role for neurokinin substance P and mast cell interaction in stress-related hair follicle changes.
17 citations
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April 2020 in “Dermatology and Therapy” In this randomized double-blind study, 160 adults with alopecia areata showed significant improvements in hair loss severity after using a bioactive peptide cosmetic product that mimics platelet-rich plasma, while the placebo group showed no significant change, underlining the treatment's potential effectiveness.
6 citations
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October 2018 in “Drug safety - case reports” In this report, two women treated with alitretinoin experienced persistent curling of their previously straight hair, suggesting a likely causal link between the medication and hair texture changes.
48 citations
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May 2015 in “NPJ microgravity” In this study, mice exposed to prolonged space conditions demonstrated skin atrophy, altered hair follicle cycles, and significant changes in the gene expression associated with skin muscle health.
January 2024 in “Wiadomości Lekarskie” In this lecture, Dr. Anna Gorecka and Dr. Ewa Bieber discuss how social media has influenced the rise of cosmetic surgery and patient expectations, as well as its connection to self-esteem and body dysmorphic disorder. Results are not reported in this summary.
January 2024 in “Wiadomości Lekarskie” This study highlights that restrictive abortion laws, financial barriers, and lack of sexual education are major issues in countries like Poland, the USA, and Italy, suggesting needed changes such as improved sex education, access to contraception, and international networks for legal abortion.
291 citations
,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
98 citations
,
October 2012 in “Dermatologic Clinics” This article reviews the impact of nutritional deficiencies on hair health, detailing how they can cause structural abnormalities, pigmentation changes, or hair loss; it presents no new clinical findings.
40 citations
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February 1990 in “Journal of The American Academy of Dermatology” This study presents the first reported case of woolly hair nevus appearing during adolescence, with significant improvement observed 5 years later and structural changes in the hair documented.
32 citations
,
January 2007 in “KARGER eBooks” This review discusses severe insulin resistance syndromes, highlighting their diagnostic challenges, potential novel therapies like leptin replacement, and suggests metformin and lifestyle changes in its absence; no new clinical results are reported.
13 citations
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December 2001 in “Dermatologic therapy” This review discusses the clinical presentations of alopecia areata, introduces guidelines for treatment studies, and explores potential changes in cutaneous innervation, but reports no new clinical results.
7 citations
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March 2018 in “Asian-Australasian journal of animal sciences” This study observed that the OCIAD2 and DCN genes in Liaoning cashmere goats have opposite effects on hair growth by interacting with the TGF-β signaling pathway, influencing follicle morphogenesis and periodic changes.
In this case report, researchers documented a 19-year-old male professional athlete with acquired trichorrhexis nodosa, noting environmental factors like chlorine exposure during swimming may have contributed to his condition, which improved after advice on hair care changes.
January 2024 in “GeroScience” This review explores how radiation-induced hair graying can be used as a model to study the mechanisms behind hair graying, focusing on cellular senescence and potential therapeutic targets to address age-related changes. Results are not provided.
June 2023 in “International Journal of Research in Dermatology” This study observed a high prevalence of severe markers among pediatric alopecia areata patients, identifying AA subtotalis as more frequent, with nail changes and various hair markers suggesting progression to severe forms.
62 citations
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October 1999 in “Journal of Investigative Dermatology” New mutations in hair keratin genes can change hair structure and cause monilethrix, with nail issues more common in certain gene mutations.
November 2024 in “Journal of Investigative Dermatology” Genetic changes in specific proteins contribute to hair loss in some women of African descent.
2 citations
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June 2024 in “Journal of Clinical Medicine” This study identifies various nail changes in alopecia areata, which can affect quality of life, and suggests that while spontaneous improvement is possible, further research is needed to refine treatment strategies.
77 citations
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June 2002 in “Journal of Investigative Dermatology” CD44 variant changes start alopecia areata, but don't maintain it.
20 citations
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November 2003 in “American Journal Of Pathology” Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
31 citations
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December 2010 in “Journal of the American Academy of Dermatology” This study reports that structural abnormalities in the inner root sheath of hair follicles may cause the hair shaft to be loosely attached in patients with loose anagen hair syndrome.