February 2025 in “Gastroenterology” Corticosteroids improved symptoms in a man with Cronkhite-Canada Syndrome.
February 2025 in “Indian Dermatology Online Journal” This case report describes a rare occurrence of pincer nail deformity in a patient with systemic lupus erythematosus, potentially linked to Raynaud's phenomena as a contributing factor.
This study analyzed scalp hair proteins from healthy children and their mothers, finding that non-structural proteins could serve as promising biomarkers for understanding long-term developmental changes and health status linked to early childhood experiences.
January 2023 in “Indian dermatology online journal” This case report discusses a 15-year-old boy with pachyonychia congenita, identifying a keratin 17 gene mutation, and highlights the need for a national registry and more accessible genetic testing in India.
November 2012 in “Hair transplant forum international” This article discusses Dr. Rajput's study on body dysmorphic disorder in hair loss patients and their improvement post-hair restoration, but it presents no original findings itself.
40 citations
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June 2021 in “Clinical, cosmetic and investigational dermatology” This review explores the efficacy and outcomes of using JAK inhibitors for treating alopecia areata, noting advancements in understanding the disease's pathomechanisms and suggesting that JAK inhibitors may offer targeted therapeutic benefits by blocking specific inflammatory pathways involved in this chronic condition.
3 citations
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July 2024 in “Frontiers in Medicine” This study reports that analyzing the clinical manifestations of different genetic variants in EBS families helps predict disease progression and severity, guide complication risk assessment, and plan necessary medical care.
3 citations
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December 2022 in “Nutrients” This study found that limonin may promote hair growth by enhancing anagen signaling through autophagy activation in rat dermal papilla cells, suggesting its potential as a natural treatment for hair loss.
2 citations
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January 2017 in “AIMS cell and tissue engineering” This review discusses the potential of mesenchymal stem cell therapies for treating various skin diseases, including vitiligo, alopecia, and epidermolysis bullosa, but reports no new results.
November 2025 in “Indian Dermatology Online Journal” This case report describes a patient with Clouston syndrome who developed squamous cell carcinoma, highlighting the need for regular follow-up in patients with chronic paronychia that do not respond to conventional treatments.
74 citations
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October 2012 in “The American Journal of Human Genetics” This study found that loss-of-function mutations in the HOXC13 gene cause autosomal-recessive pure hair and nail ectodermal dysplasia, emphasizing its role in hair and nail development.
68 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests a regulatory model where HOXC13 activates Foxn1, affecting hair and nail differentiation, supported by similarities in Hoxc13(tm1Mrc) and Foxn1(nu) mice phenotypes and gene expression patterns.
38 citations
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January 2012 in “Journal of Korean Medical Science” This study found that early-onset patients with alopecia universalis or a family history of alopecia areata showed worse prognosis compared to those with late-onset.
25 citations
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August 2020 in “Experimental eye research/Experimental Eye Research” This review discusses cornea-specific keratin expression patterns in human and mouse development and reports no new experimental results; it highlights the need for investigating keratin mutations' role in pathology.
22 citations
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January 2009 in “Advances in experimental medicine and biology” This review discusses the human Nude/SCID phenotype and FOXN1 gene's role in immunological disorders affecting T-cell development but reports no new clinical findings.
2 citations
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May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study describes a family where a TP63 mutation was linked with prominent alopecia and mild ectodermal dysplasia features.
April 2023 in “International journal of molecular sciences” This study found that scalp disorders, such as hair loss and itching, can be associated with collagen VI mutations, thus highlighting the need to investigate scalp involvement in these patients.
March 2014 in “Hair transplant forum international” This article discusses the evolving field of hair transplantation surgery and reports no new experimental results, highlighting ongoing developments aimed at improving procedural success and doctor efficacy.
September 2025 in “Journal of Cosmetic Dermatology” This review found that hair transplantation can positively impact self-esteem and emotional well-being when patients are properly screened for psychological risk factors, but inadequate screening may lead to dissatisfaction or worsened mental health.
February 2018 in “InTech eBooks” This review discusses the role of platelet-rich plasma therapy in various cosmetic procedures, finding potential benefits in improving tissue homeostasis if harvesting standards are maintained, but reports no new clinical results.
28 citations
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April 1996 in “Cell biology international” This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.
47 citations
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May 2002 in “Journal of Cutaneous Medicine and Surgery” This review discusses normal skin changes during pregnancy such as pigmentary and glandular alterations, highlighting the need for physician awareness to avoid unnecessary treatments, and reports no new clinical findings.
In this study, researchers used two dermal papilla spheroid models to investigate hair cycle regression mechanisms and found that the vascular system enhances tissue physiology and gene modulation, while Retinol-based treatments can partially recover tissue degeneration observed over an extended culture period.
1 citations
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January 2013 in “Springer eBooks” The document concludes that skin and nail changes can indicate various underlying health conditions.
19 citations
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January 2018 Most people with alopecia areata have nail changes, which are common but don't greatly affect their quality of life.
16 citations
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July 2021 in “Histopathology” This review discusses recent findings on molecular changes in cutaneous adnexal tumours and reports novel markers and pathways involved, highlighting the diverse oncogenic drivers and tumour suppressor alterations.
124 citations
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August 1994 in “Journal of Investigative Dermatology” This study found that applying dexamethasone to mice induced catagen-like follicle changes significantly earlier and more consistently than a vehicle, such changes being useful for studying hair follicle regression.
9 citations
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April 2018 in “Journal of Dermatological Treatment” This study found that oral tofacitinib monotherapy improved nail changes in 73.3% of adults with moderate-to-severe alopecia areata over a median period of 5 months, but nail improvement was not linked to the severity of hair loss or hair regrowth.
1 citations
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April 2020 in “Magnetic Resonance in Medical Sciences” This study aimed to determine if MRI can assess anatomical changes in the scalp caused by androgenetic alopecia, but it reports no new clinical results.
March 2022 in “International Journal of Current Science Research and Review” This article describes subclinical ketosis in pregnant cows and associates it with several metabolic changes and clinical signs, reporting decreased levels of hemoglobin and glucose and increased ketone bodies.