March 2025 in “International Journal of Advanced Research in Science Communication and Technology” This study explores the potential of herbal hair dyes as eco-friendly alternatives to synthetic dyes, highlighting their natural coloring ability and additional benefits like scalp nourishment and hair strengthening, while evaluating factors such as pH, spreadability, and color fastness.
April 2024 in “Pharmacognosy research” In this study, researchers developed a herbal hair dye using henna and other natural ingredients that achieved a color similar to natural black on blonde hair, though further testing on various hair shades is needed to explore its full benefits.
This study evaluated various herbal blends of powdered leaves, including Henna and Indigo, for their coloring and sensitivity reactions, finding Henna and Indigo to be effective natural colorants for achieving a reddish-brown hair color with better retention than marketed herbal hair dyes.
November 2023 in “Journal of cosmetic dermatology” This report describes three cases of erythromelanosis follicularis faciei et colli showing significant improvement in facial telangiectasia following treatment with a 595-nm pulsed dye laser, with minimal recurrence observed during follow-up.
October 2023 in “Biomimetics” This study developed a biocompatible hair-dyeing technology using a dark polyphenol complex, which demonstrated effective hair coating, improved mechanical strength, and strong antioxidant properties while maintaining high cell viability.
August 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated various herbal combinations for hair coloring and found that a formulation of Henna and Indigo provided a natural reddish-brown color with better retention compared to marketed herbal hair dyes, without using synthetic agents that can cause allergic reactions.
March 2021 in “International journal for research in applied science and engineering technology” In this study, researchers explored the use of natural herbal hair dyes made from tannin-producing plants like henna and pomegranate, reporting that these dyes can permanently color hair without causing damage or irritation, unlike synthetic dyes.
May 2017 in “Journal of The American Academy of Dermatology” 595 nm pulsed dye laser is a cost-effective treatment for nonmelanoma skin cancer with a low recurrence rate.
August 2013 in “Toxicology letters” 69 citations
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January 2002 in “Journal of biomedical optics” This study found that commercially available dyes penetrate up to 1.2 mm into human skin, with Indocyanine Green binding to cell proteins and showing a shift in absorption peak.
21 citations
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January 1995 in “Journal of the American Institute for Conservation” This study describes a new method for extracting red mordant dyes from wool fibers using ethylene diamine tetraacetic acid and N,N-dimethyl formamide, preserving the fibers for further examination.
17 citations
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May 2019 in “Molecules” This study found that domestic temporary hair dyes may pose a health risk due to their cytotoxic effects on human red blood cells and NIH/3T3 cell lines.
8 citations
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January 2016 This study concluded that replacing the synthetic dye Sunset Yellow with curcumin as a colorant in foods may avoid cytotoxic and genotoxic effects observed in mice.
44 citations
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April 2003 in “European journal of pharmaceutical sciences” This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.
34 citations
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January 2012 in “Journal of Dermatological Science” In this mouse study, researchers found that hydrogen peroxide and monoethanolamine in hair dyes may be key contributors to dermatitis and hair loss due to oxidative stress.
24 citations
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April 2016 in “Experimental Dermatology” This study found that chemical treatments like perming, dyeing, and bleaching significantly alter amino acids and lipids in human hair, which may impact hair strength and quality.
5 citations
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November 2003 in “PubMed” This study found that chemical and photochemical oxidative processes modify the main classes of proteins in hair, confirmed through microspectrophotometric, fluorescence microscopy, and electrophoretic methods.
In this study, penetration of FA-PLGA nanoparticles into hair follicles was observed in excised dog, rat, and porcine skin, with the deepest penetration in porcine skin, suggesting its similarity to human skin for drug delivery studies.
48 citations
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May 2021 in “Molecules” The researchers found that plant extracts from Papaver rhoeas L., Clitoria ternatea L., and Carthamus tinctorius L. are effective natural cosmetic dyes, offering intense and stable colors without cytotoxicity.
1 citations
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June 2025 in “International Journal of Plant and Environment” This study found that nickel oxide nanoparticles synthesized using Alternanthera sessilis extract may have potential as antimicrobial, antifungal, and dye-removal agents.
157 citations
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April 1997 in “International journal of legal medicine” This study found that cosmetic hair treatments like bleaching and dyeing significantly reduced drug concentrations in hair samples, with decreases ranging from 30% to over 60% depending on the treatment and hair damage level.
46 citations
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January 2009 in “Textile Research Journal” This study presents a DNA-analytical method that can reliably identify and differentiate cashmere, fine wool, yak, and camel hair fibers in both untreated and processed samples.
25 citations
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November 2014 in “British Journal of Dermatology” This study found various ABC transporters are transcribed in human hair follicles, suggesting their possible role in HF biology and potential for new therapeutic interventions.
18 citations
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July 2015 in “Journal of cosmetic dermatology” This study observed that combining hair dyeing with sodium hydroxide relaxers drastically increased protein loss in Caucasian virgin dark brown hair, while ammonium thioglycolate or guanidine hydroxide relaxers caused less damage.
15 citations
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June 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that bleaching, dyeing, and UVA/Vis radiation caused significant cuticle damage and protein loss in both Caucasian and Afro-ethnic hair, highlighting the aggressive nature of these treatments.
14 citations
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September 1954 in “Textile Research Journal” This study found that hair absorbs significant amounts of NaBr from solution, with absorption increasing linearly with solution concentration and additional effects noted with acidic or basic solutions.
8 citations
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February 2022 in “International Journal of Dermatology” This review discusses the lipid composition of human hair across ethnic types, effects of damage on lipid content, and associated changes with diseases, but reports no new findings; further research is needed.
7 citations
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January 1995 This study found that using a high-viscosity, high-amine-content silicone fluid as a pretreatment can protect hair from bleaching and dyeing damage without affecting these processes.
3 citations
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February 2023 in “ACS omega” In this study, grape seed oil was found to be the most effective herbal oil for improving gloss and reducing fractures in various hair types.
3 citations
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October 2006 in “Journal of dermatology” This study reported that X-ray microscopy provides more intact images of hair's internal structure compared to transmission electron microscopy, particularly for observing fine details like cuticle coarsening and cortex cracks.