August 2022 in “Contact dermatitis” This case report describes a 24-year-old male who developed alopecia areata following an allergic reaction to a permanent hair dye, possibly linked to previous sensitization from a henna tattoo.
June 2021 in “Journal of emerging technologies and innovative research” This article reviews the potential hair-protective effects of Onion and Aloe vera against damage from hair dyes but reports no new experimental results.
January 2019 in “Dermatologic Surgery” This source outlines the Dermatologic Surgery journal, which provides extensive and up-to-date information on diverse dermatologic surgical procedures and skin cancer treatments, featuring peer-reviewed articles, literature reviews, and case reports valuable to professionals like dermatologists and plastic surgeons.
November 2016 in “University of the Arts London Research Online (University of the Arts London)” This study concluded that adding polymeric conditioning actives to shampoos improved color retention in permanently dyed hair, while additional cationic dyes at certain pH levels weakly dyed the hair directly.
February 2009 in “Journal of The American Academy of Dermatology” This study suggests that fractional infrared technology may effectively improve cervical skin laxity by enhancing dermal thickness without adverse effects in a small pilot group.
December 1990 in “Indian Journal of Dermatology Venereology and Leprology” Topical minoxidil and hair dye can improve hair density and appearance in congenital hypotrichosis.
December 1988 in “Anatomia, Histologia, Embryologia” In this study, eight healthy dogs showed hair and skin damage, including hair shaft fractures and skin irritation, after repeated application of Clairol Hair Dye Flaxen Blonde.
August 1985 in “Proceedings ... annual meeting, Electron Microscopy Society of America/Proceedings, annual meeting, Electron Microscopy Society of America” This study investigated the effects of intensive hair dye use in mixed-breed dogs and found changes in the cuticle of the hair shaft and the epidermis using scanning electron microscopy.
August 2024 in “Journal of the Korean Society of Cosmetology” The research reported that applying treatments with wild peach leaf extract during hair dyeing improved hair's tensile strength, thickness, gloss, and protective qualities in a concentration-dependent manner, suggesting potential for use in natural hair cosmetics.
August 2024 in “International Journal of Cosmetic Science” This study found that acetyl zingerone methyl ether (MAZ) in hair dyes and haircare products may reduce oxidative damage, improve hair condition, and enhance the longevity and quality of dyed hair color.
79 citations
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January 1975 in “Food and Cosmetics Toxicology” In this study, oxidation hair dye formulations tested on mice showed no evidence of causing systemic toxicity or cancer over an 18-month period.
24 citations
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January 2001 in “International Journal of Cancer” This study from Los Angeles supports the idea that using permanent hair dye may increase bladder cancer risk in US women, especially those with a slow NAT2 acetylation phenotype.
12 citations
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December 2017 in “Food and chemical toxicology” This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.
10 citations
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January 2015 in “Current problems in dermatology” This chapter provides dermatologists with hair care guidance for alopecia patients and emphasizes that improper handling and chemical processing can worsen hair loss, though it reports no new clinical findings.
9 citations
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July 2022 in “Journal of Cosmetic Dermatology” In this study, an ammonia-free and PPD-free permanent hair dye was tested on 50 ethnically diverse females, showing no cases of contact dermatitis and significant improvements in hair shine, color, moisturization, porosity, and combability after two dyeing sessions.
6 citations
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January 2020 in “Elsevier eBooks” Nanoparticles could make hair dyes safer by reducing harmful effects.
4 citations
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January 2016 in “Skin research and technology” This study found that oxidative hair dyes altered the color and ultrastructure of Caucasian hair but did not significantly affect the hair's breaking strength.
2 citations
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November 2025 in “Comprehensive Reviews in Food Science and Food Safety” This review discusses the growing role of colorimetric sensors in food safety, highlighting their potential to enhance detection accuracy and manageability, while also noting challenges such as environmental interference and the need for further industrial validation.
1 citations
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June 2023 in “Skin Research and Technology” This study found that two shampoos with different dyeing methods had varying abilities to dye hair and impact hair health, suggesting that individuals should select hair color shampoos based on their personal needs.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and evaluated an herbal hair dye using extracts from plants like henna and amla, which possess antibacterial and antioxidant properties, and found favorable results through various tests such as organoleptic and physico-chemical evaluations.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study prepared a herbal hair dye using extracts from various herbs like Ratanjot, Henna, and Amla, known for their antibacterial and antioxidant properties, and evaluated its characteristics and effects through organoleptic and physico-chemical assessments, among other tests.
June 2026 in “Applied and Computational Engineering” This study reviewed the principles and classifications of hair dyes, identifying significant differences between oxidative, temporary non-oxidative, and semi-permanent non-oxidative dyes in terms of duration, application methods, and potential risks, which could help improve safety and convenience in hair dye use.
This study developed a natural hair dye using Coreopsis tinctoria Nutt. extract, finding that it produced yellow to dark brown colors depending on the treatment, with ferrous lactate enhancing dye performance and color stability after washing.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a herbal hair dye gel using natural ingredients like henna and amla, which was found to provide natural color, improve hair texture, and clean the scalp without causing irritation, making it a safe and effective alternative to chemical hair dyes.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a herbal hair dye gel made from natural ingredients like henna and amla showed promising results in providing natural color and hair health benefits without causing irritation, offering a safer alternative to chemical hair dyes.
May 2026 in “International Journal of Research Publication and Reviews” The researchers reported that a polyherbal hair dye using Phyllanthus reticulatus fruit provided effective color, stability, and scalp compatibility without irritation, positioning it as a safe and eco-friendly alternative to synthetic dyes.
April 2026 in “Cosmetics” This study developed and tested a shampoo with semi-permanent dyes designed to gradually cover gray hair, reporting maintained stability and effective gray–black coloration on high-canities hair tresses through eight wash cycles.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit and other natural ingredients, reporting that the dye provided satisfactory color, stability, scalp pH compatibility, and did not cause irritation, also demonstrating antioxidant and antimicrobial properties that benefit scalp health.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit, finding it to be a safe, effective, and environmentally friendly alternative to synthetic dyes, with added antioxidant and antimicrobial benefits for scalp health.
December 2025 in “Sustainable Chemistry One World” In this study, researchers found that mangosteen pericarp extract, combined with FeSO₄ as a mordant, effectively produced a stable reddish hair dye on bleached hair, with good color persistence and enhanced tensile strength, indicating its potential as an eco-friendly and safer alternative to synthetic dyes.