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research Issue Information
This abstract provides issue information for the Dermatologic Therapy journal's November/December 2016 edition and offers no new study results.
research DNN-DTIs: improved drug-target interactions prediction using XGBoost feature selection and deep neural network
This study found that the DNN-DTIs prediction model achieved high accuracy in predicting drug-target interactions, suggesting its potential application in drug repositioning and the discovery of new uses for existing drugs.
research O-T-C Hair Preparations
research Tineas—Superficial Dermatophyte Infections
This article reviews the characteristics and treatment options for various dermatophyte infections, highlighting that systemic treatment is essential for tinea capitis while topical treatments are generally effective for other types.
research Impulse Control Disorders
This review discusses various aspects of Impulse Control Disorders, but reports no new clinical findings; the authors highlight existing knowledge gaps and the need for proven treatments.
research Artificial Intelligence in Dermatology: Assessing Predictability in Clinical Diagnosis
In this study, the Tibot AI application showed high diagnostic accuracy for adnexal and pigmentary disorders and cutaneous tumors in dermatology, but was less effective for immunological disorders and infestations, suggesting the need for further dataset refinement.
research Trichothiodystrophy and fragile hair: the distinction between diagnostic signs and diagnostic labels in childhood hair disease
This study suggests that clinically apparent fragile hair in children is rarely linked to trichothiodystrophy, and the tiger-tail pattern is not wholly specific to this diagnosis.
research LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants
TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.
research 50570 Irritation and sensitization potential of approved topical and transdermal delivery systems – A retrospective study
Generic topical and transdermal systems usually cause minimal irritation or sensitization.
research Dacomitinib-Induced Paronychia Associated With PRIDE Syndrome in a Patient With Non-Small Cell Lung Cancer
This case study documents a 55-year-old male with advanced NSCLC who experienced toe-predominant paronychia and a papulopustular rash following dacomitinib treatment, with the causality tools indicating a "probable" link, yet the therapy continued successfully without dosage alteration.
research Index
This handbook of dermatology provides a comprehensive practical manual for dermatologists, but reports no new research findings.
research Diagnosis of Trichothiodystrophy in 2 Siblings
This case report details two siblings with trichothiodystrophy, identifying reduced hair sulfur content as essential for diagnosis despite varied symptoms complicating recognition.
research Direct‐to‐consumer healthcare and its expanding role in the Australian healthcare system
This study emphasizes the need for a formal evaluation of direct-to-consumer telemedicine services in Australia to ensure safety, privacy, and ethical standards while maintaining high-quality healthcare.
research Subject Index
research Subject Index
research Phase II Evaluation of VDC‐1101 in Canine Cutaneous T‐Cell Lymphoma
This study found that the novel drug VDC-1101 showed a 45% objective response rate in treating canine cutaneous T-cell lymphoma, offering a potential treatment option for this challenging disease.
research Allergic and irritant contact dermatitis compared in the treatment of alopecia totalis and universalis. A comparison of the value of topical diphencyprone and tretinoin gel
In this study, the authors compared topical diphencyprone and tretinoin gel for treating alopecia totalis and universalis, but the abstract does not report any definitive clinical results.
research 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin causes an increase in protein kinases growth hepatic associated with epidermal factor receptor in the plasma membrane
In this study, TCDD administered to male rats down-regulated EGF receptor in liver plasma membranes and increased protein kinase activity, suggesting EGF receptor–mediated toxicological effects.
research Trichoscopy of dissecting cellulitis of the scalp: Exclamation mark hairs and white dots as markers of disease chronicity
This article discusses the potential of trichoscopy in diagnosing and treating dissecting cellulitis of the scalp and emphasizes the need for early diagnosis to prevent progression but reports no new clinical results.
research TOPICAL IMMUNOTHERAPY IN DERMATOLOGY
This review discusses the use of topical immunotherapy for severe alopecia areata and resistant viral warts, highlighting diphencyprone's advantages and the need for careful handling to avoid staff sensitisation; it reports no new clinical results.
research LB943 Tofacitinib treatment of inflammatory skin conditions in patients with Down Syndrome
In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.
research The Cross-section Trichometer: A New Device for Measuring Hair Quantity, Hair Loss, and Hair Growth
This study developed a prototype device that suggests potential for diagnosing changes in hair quantity, diameter, and density, though formal clinical studies are needed to confirm these findings.
research Biotin and biotinidase deficiency
This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.
research Dynamic Trichoscopy
This Viewpoint discusses the utility of dermoscope in routine practice and how familiarity with dynamic vs static trichoscopy may address its limitations, but it reports no new clinical findings.
research Diagnostic value of trichoscopic findings of hair and scalp in dissecting cellulitis: case report and review of the literature
In this case study, trichoscopy was found to be a valuable non-invasive tool for diagnosing dissecting cellulitis of the scalp, enabling early detection and intervention to prevent disease progression and reduce the need for invasive procedures.
research Tricotiodistrofia. Reporte de un caso
This case report describes a 2-year-old boy diagnosed with trichothiodystrophy, characterized by fragile hair, intellectual damage, diminished fertility, and short stature.
research Index
This abstract is a list of dermatological conditions and treatments without providing new research findings or clinical results.
research Temporal triangular alopecia and a review of 52 past cases
This review provides a synopsis of 53 cases of temporal triangular alopecia, noting its frequent detection in early childhood and potential association with congenital diseases, but it reports no new clinical findings.
research Clinical recognition and therapeutic treatment options for cutaneous epitheliotropic lymphoma in dogs
This case report highlights that cutaneous epitheliotropic lymphoma in dogs can present with various skin lesions, such as depigmentation, making diagnosis challenging for veterinarians.