8 citations
,
January 2015 in “Scars, burns & healing” This review discusses surgical and non-surgical options for hair restoration in burn alopecia, highlighting follicular unit extraction and transplant as preferred methods but reports no new clinical findings.
7 citations
,
January 2021 in “Dermatology and therapy” This study confirmed that the Alopecia Areata-Investigator Global Assessment and other clinical outcome assessments are valid and relevant measures of treatment success for alopecia areata patients in Japan, aligning with previous North American findings.
7 citations
,
December 2014 in “Gynecological Endocrinology” This study found that LC-MS/MS is a more reliable method than immunoassays for measuring serum 17OHP and androgen levels in women with hyperandrogenism.
7 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses the indications and technical aspects of megasession hair transplantation and reports no new clinical results.
3 citations
,
October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that scalp hair loss is the most bothersome symptom of alopecia areata for both adults and adolescents, highlighting the need for treatments focused on improving scalp hair growth.
2 citations
,
November 1998 in “Journal of The European Academy of Dermatology and Venereology” This study focused on the ultrastructural and immunohistochemical aspects of dermal mast cells in systemic mastocytosis and their interaction with the epidermal melanin unit.
1 citations
,
September 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” This source discusses the potential of topical JAK inhibitors, like tofacitinib, as effective treatments for autoimmune skin diseases, emphasizing their superior safety profile and minimal adverse effects compared to conventional systemic therapies.
1 citations
,
November 2017 in “Dermatologic clinics” This review discusses common male cosmetic procedures often performed in combination but provides no new clinical results; it shares the author's experience and suggests potential benefits of combining therapies.
1 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article reviews the evolution and advancements in hair restoration techniques over the past 20 years, emphasizing the shift from "plug" methods to natural-looking follicular unit grafts, but reports no new experimental results.
This study presents a two-photon imaging method to visualize low-threshold mechanoreceptor axon terminals in live mouse forepaw skin, enabling repeated high-resolution imaging to study sensory circuits during development and adulthood.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in mice, competition for hair follicles guides the organization of follicle-innervating LTMR neurons during early development, with different neuronal subtypes showing varying adaptive responses to increased neuron populations.
June 2020 in “Journal of Investigative Dermatology” This study observed that human primary adult hair matrix keratinocytes may have the potential to generate hair follicle organoids, suggesting possible applications in hair follicle neogenesis and preclinical hair growth agent screening.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that miR-486 may protect against alopecia areata by maintaining hair follicle immune privilege and modulating expression of immune-related genes.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” In a laboratory setting, this study found that Biotrinine® dry extract activated hair follicle growth pathways and increased certain growth factor secretions in human dermal papilla cells, suggesting potential benefits for treating chronic hair loss.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that Ginseng and Albizia extracts, when used together, protected human dermal papilla cells from oxidative stress-induced senescence, and inhibited genes that suppress hair growth, indicating their potential in preventing age-related hair density reduction.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that low-dose blue light (453nm) may positively affect hair growth by interacting with the receptors CRY1 and OPN3 in hair follicle cells.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that mitochondrial dysfunction might contribute to the pathogenesis of Lichen planopilaris by triggering a metabolic shift that leads to chronic inflammation and hair follicle damage.
January 2012 in “Methods in pharmacology and toxicology” This review discusses the expanding understanding of TRPV3's role in pain and skin pathology, while highlighting the need for further pharmacological research to fully resolve its functions.
September 2024 in “The Indian Veterinary Journal” This case report describes a three-month-old male Labrador pup with dermatophytosis, diagnosed through clinical signs and a Woods lamp test, which successfully recovered from the infection with a four-week treatment regimen involving topical and oral therapies.
August 1978 in “Dicp-The annals of pharmacotherapy” Mannitol diuresis allows higher doses of cis-platinum for testicular cancer treatment without increasing kidney damage.
72 citations
,
December 2009 in “Organic and Biomolecular Chemistry” This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.
29 citations
,
August 2007 in “Annals of Oncology” Docetaxel and oxaliplatin are effective and have manageable side effects for recurrent platinum-sensitive ovarian cancer.
4 citations
,
March 2009 in “British Journal of Dermatology” This article discusses the highlights and key topics from the 17th Congress of the European Academy of Dermatology and Venereology but reports no new results.
1 citations
,
April 2016 in “British Journal of Dermatology” Buschke-Ollendorff syndrome is a rare genetic disorder causing skin and bone changes, with some cases also showing ADHD or developmental delays.
508 citations
,
February 2007 in “Cell” This article reviews the biology of epithelial stem cells and their role in tissue self-renewal, maintenance, and regeneration, and it highlights the clinical implications of understanding their signaling pathways, but it presents no new clinical findings.
396 citations
,
May 2011 in “Cell stem cell” This study found that Shh from neurons signals to Gli1-expressing cells in the hair follicle, cultivating a niche where these bulge cells can potentially transform into epidermal stem cells in wound healing.
330 citations
,
December 2009 in “Cell stem cell” This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.
142 citations
,
September 2020 in “Journal of neurophysiology” This study estimates that young adults have about 230,000 tactile afferent fibers innervating their skin, with density varying by region and decreasing with age.
124 citations
,
December 2016 in “Pharmaceuticals” This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.
115 citations
,
November 2004 in “Brain Behavior and Immunity” This study found that stress increases the number of peptidergic nerve fibers and mast cell activity in mouse skin, suggesting a significant neuro-immune interaction under stress.