research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
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research 5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction
Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
research Dopamine Is a Novel, Direct Inducer of Catagen in Human Scalp Hair Follicles In Vitro
Dopamine stops hair growth and pigment production in human scalp hair follicles.
research Telogen Effluvium Associated with the Dopamine Agonist Pramipexole in a 55-Year-Old Woman with Parkinson's Disease
A woman with Parkinson's disease experienced hair loss from the Parkinson's medication pramipexole, which improved after stopping the drug.
research Finasteride Inhibited Brain Dopaminergic System and Open-Field Behaviors in Adolescent Male Rats
Finasteride affects young male rats' brain function and behavior negatively.
research Fetal Environment-Simulating Hyaluronic Acid-Dopamine-Chondroitin Sulfate Hydrogel Promoting Angiogenesis and Hair Regeneration for Wound Healing
The hydrogel helps heal wounds and regrow hair by mimicking a baby's environment.
research Effects of Dobutamine on Cyclic AMP Accumulation Induced by the Stimulation of Dopamine Receptors in Rabbit Retina In Vitro
Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.
research Neonatal Finasteride Administration Decreases Dopamine Release in Nucleus Accumbens After Alcohol and Food Presentation in Adult Male Rats
Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.
research Epigenetic Effects of Finasteride on Dopaminergic Signaling Pathways: A Potential Contributor to Post-Finasteride Syndrome
Finasteride may cause changes in dopamine-related genes, possibly leading to post-finasteride syndrome.
research Hair Loss: An Overlooked Nonmotor Symptom in Parkinson’s Disease During Dopaminergic Therapy
Dopaminergic therapy in Parkinson's disease patients is linked to increased hair loss.
research Allopregnanolone Is Required for Prepulse Inhibition Deficits Induced by D1 Dopamine Receptor Activation
Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
research Progesterone Enhances Ethanol-Induced Modulation of Mesocortical Dopamine Neurons: Antagonism by Finasteride
Progesterone boosts alcohol's effect on brain, finasteride counters it.
research The Effects of Acute Finasteride Treatment in Dopamine Transporter Knockout Mice and MK-801-Treated Mice
research Minoxidil Overdose With Hypotension Effectively Managed With Norepinephrine, Rather Than Dopamine
research Determining the Relationship Among Cattle Genotype, Hair Coat Score, and Productivity Through the Investigation of Single Nucleotide Polymorphisms Within Prolactin, Dopamine Receptor D2, and Melatonin Receptor 1A
research Trichotillomania as a Manifestation of Dementia
Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.
research News on PCOS
Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.
research The Neurobiology of Sexual Function
Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
research Abnormal Neuronal Differentiation and Mitochondrial Dysfunction in Hair Follicle-Derived Induced Pluripotent Stem Cells of Schizophrenia Patients
Schizophrenia patients' stem cells show abnormal neuron development and mitochondrial issues.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase
Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
research Polycystic Ovary Syndrome and Its Differential Diagnosis
The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
research Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two Sides of the Same Coin?
PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
research Finasteride Attenuates Pathological Gambling in Patients With Parkinson's Disease
Finasteride reduces gambling symptoms in Parkinson's patients.
research Hedonic Sensitivity to Natural Rewards Is Affected by Prenatal Stress in a Sex-Dependent Manner
Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
research Effect of the 5α-Reductase Enzyme Inhibitor Dutasteride in the Brain of Intact and Parkinsonian Mice
Dutasteride may protect the brain in early Parkinson's disease.
research Steroid 5α-Reductase 2 Deficiency Leads to Reduced Dominance-Related and Impulse-Control Behaviors
Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
research Exploring the Neural Mechanisms of Finasteride: A Proteomic Analysis in the Nucleus Accumbens
Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
research Utilizing the Hair Follicle to Dissect the Regulation and Autocrine/Paracrine Activities of Prolactin in Humans
Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.
research Minoxidil Overdose: Severe Hypotension and Tachycardia After Ingestion
Man drank minoxidil, caused low blood pressure and fast heartbeat, treatment helped but led to heart damage.