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Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Mutations in certain receptors can cause diseases and offer new treatment options.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.