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PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Polyamines help fix DNA damage accurately in cells.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Researchers improved a method to study individual cells in newborn mouse skin and found a way to assess the severity of a skin condition in humans.

Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.

Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.

ALRN-6924 may prevent hair loss caused by chemotherapy.

Exosomal miRNAs from stem cells can help improve skin health and delay aging.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

EGFR helps control how hair grows and forms without needing p53 protein.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

Higher minoxidil dose helps hair growth in non-responders without side effects.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.