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TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

LAAM caused developmental toxicity in tolerant rats without causing birth defects.

Finasteride may affect PNMT, causing side effects.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Older patients sticking to their prostate medication saw lasting health benefits.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Finasteride may effectively reduce Tourette's syndrome symptoms and improve life quality.

Dutasteride improved hair density and thickness in men not helped by finasteride, with minimal side effects.

Finasteride's negative effects on brain tissue in male rats may be reversible after stopping the drug.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Suppressing certain hormones might help prevent prostate cancer.