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Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

The research found specific genes and pathways that control fur development and color in young American minks.

Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.

Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.

The tobacco leaf extract may help hair grow and could treat hair loss.

The meeting presented findings on effective treatments for various pet skin conditions and insights into the immune responses of dogs with atopic dermatitis.

Inhibiting ODC can prevent UV-induced skin cancer.

Obesity is linked to more severe lower urinary tract symptoms.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Men with male pattern baldness have higher blood sugar, bad cholesterol, and ZAG protein levels than healthy men.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.

Massaging the scalp with a cosmetic containing certain natural inhibitors can significantly regrow hair in men with pattern baldness.

Women with PCOS may have a reduced ability to fight breast tumor cells over time.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Finasteride and minoxidil together promote hair growth better than either alone.

Finasteride reduces hair growth and is safe for women with excessive hair.

Finasteride doesn't affect hormone levels in normal men.

Rats had lasting erectile problems after stopping a certain medication.

High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Finasteride doesn't affect erections much, but may decrease libido in men.