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JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

Some minoxidil combinations can help differentiate leukemia cells without harming other cells.

Three dogs with a rare skin condition improved with treatment.

Treating psoriasis with UVB light three times a week is faster than twice a week, and certain medications and lifestyle factors affect psoriasis treatment outcomes.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Stopping certain drugs can improve skin conditions, arsenicosis affects over half of a Bangladeshi village, males are more vulnerable, and certain treatments are effective for warts, acne, and psoriasis. Smoking and drinking are linked to psoriasis in men, a cream helps with a type of skin cancer, and low iron levels don't directly cause chronic hair loss in women.

Laminin 332 is essential for normal skin cell behavior and structure.

Glucosylceramides are essential for healthy skin and proper wound healing.

The substance AS101 can help hair grow by slowing down hair cell aging and boosting a hair growth protein.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Trichoscopy helps tell apart Frontal Fibrosing Alopecia and Lichen planopilaris by showing different hair and scalp features.

Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Mitochondrial reactive oxygen species are essential for skin and hair development.

Recent progress has been made in understanding inherited hair and nail disorders.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.

The document emphasizes the importance of correctly identifying and classifying genetic hair disorders to help diagnose related health conditions.

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Thyroid problems can cause hair loss and change hair texture.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Melanoma risk tools need improvement, a gene mutation causes a hair disorder that might be treated by managing cell stress, a potential therapy for a skin-ear disorder involves blocking cell channels, skin wrinkling may indicate lung aging regardless of smoking, and oxidative stress might contribute to common baldness.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.