April 2021 in “Journal of evolution of medical and dental sciences” Women with PCOS have higher levels of certain androgens, which are good at predicting excess hair growth.
June 2024 in “Journal of Cosmetic Dermatology” Higher homocysteine levels may inhibit hair growth and are linked to androgenetic alopecia.
1 citations,
March 2021 in “F1000Research” Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.
119 citations,
May 2020 in “Journal of The American Academy of Dermatology” Most COVID-19 patients in hospitals have androgenetic alopecia, more in men, suggesting a link between androgen sensitivity and severe COVID-19 symptoms.
59 citations,
January 1976 in “Vitamins and hormones” Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.
57 citations,
April 2009 in “The Journal of Steroid Biochemistry and Molecular Biology” Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
57 citations,
February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
37 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
18 citations,
January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
14 citations,
February 1998 in “Bioorganic & Medicinal Chemistry Letters” Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
12 citations,
April 1995 in “Journal of Medicinal Chemistry” The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
35 citations,
May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
1 citations,
January 2015 in “Elsevier eBooks” Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
129 citations,
January 2004 in “Journal of medicinal chemistry” Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
8 citations,
June 2017 in “Steroids” New chemical compounds were made that effectively block an enzyme linked to prostate growth.
3 citations,
May 2017 in “Bioorganic & medicinal chemistry letters” New compounds were made that are promising for prostate cancer therapy.
April 2019 in “Journal of Investigative Dermatology” Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.
11 citations,
February 2016 in “Current Medicinal Chemistry” New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
76 citations,
October 2016 in “Clinics in dermatology” Sex hormones, especially androgens, play a key role in causing acne.
31 citations,
April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
23 citations,
January 2001 in “Chemical & Pharmaceutical Bulletin” New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
20 citations,
March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
19 citations,
June 1999 in “Steroids” Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
1 citations,
November 2022 in “International Journal of Cosmetic Science” Lotus corniculatus seed extract reduces oily skin by decreasing sebum production.
October 2023 in “Journal of the American Academy of Dermatology” Clascoterone cream could be used for other skin conditions affected by hormones.
December 2022 in “CRC Press eBooks” Antiandrogens block male hormones and are not safe during pregnancy.
56 citations,
February 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
10 citations,
February 2017 in “European journal of neuroscience/EJN. European journal of neuroscience” The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.
29 citations,
November 1975 in “Clinics in endocrinology and metabolism” Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.
17 citations,
August 2011 in “Current Medicinal Chemistry” New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.