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    Glossary Dihydrotestosterone Blockers

    inhibit the hormone DHT to prevent hair loss

    Dihydrotestosterone Blockers, often referred to as DHT Blockers, are substances that inhibit the action or production of dihydrotestosterone (DHT), a hormone linked to hair loss. By reducing DHT levels, these blockers can help prevent hair follicles from shrinking, thereby slowing or stopping hair loss and promoting hair regrowth.

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    1. New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway Current Enzyme Inhibition · 2022
    2. Testosterone Reduces Knee Passive Range of Motion and Expression of Relaxin Receptor Isoforms via 5α-Dihydrotestosterone and Androgen Receptor Binding International Journal of Molecular Sciences · 2014 · 23 citations
    3. Androgenetic alopecia: An autosomal dominant disorder The American Journal of Medicine · 1995 · 80 citations
    4. Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 57 citations
    5. Comparison of clinical trials with finasteride and dutasteride. PubMed · 2004 · 20 citations
    6. Anti-androgen therapy in dermatology: a review Clinical and Experimental Dermatology · 1979 · 5 citations
    7. Focus sulla finasteride: efficacia, meccanismi e raccomandazioni per l'uso clinico Gazzetta Medica Italiana Archivio per le Scienze Mediche · 2026
    8. CAN PATIENTS WITH LUTS AND BPH DISCERN CHANGES IN PEAK URINARY FLOW RATE AND DO SUCH CHANGES CONTRIBUTE TO OVERALL SATISFACTION WITH TREATMENT? The Journal of Urology · 2009
    9. Age‐dependent regulation by androgens of gene expression in the anterior hypothalamus and stress‐induced release of adrenal hormones in adolescent and adult male rats Journal of neuroendocrinology · 2019 · 10 citations
    10. Pharmacological Profile of 9,11-Dehydrocortexolone 17α-Butyrate (CB-03-04), a New Androgen Antagonist with Antigonadotropic Activity Arzneimittelforschung · 2011 · 1 citations
    11. Androgen action on human skin – from basic research to clinical significance Experimental dermatology · 2004 · 147 citations
    12. Androgenetische Alopezie beim Mann . Male androgenetic alopecia Zeitschrift für Hautkrankheiten · 2002 · 1 citations
    13. Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes Scientific Reports · 2017 · 54 citations
    14. Androgenic modulation of arterial baroreceptor dysfunction and neuroinflammation in endotoxic male rats Brain Research · 2021 · 2 citations
    15. Phytotherapy in Trichology: A Review Brazilian Journal of Hair Health · 2025
    16. An update on the use of 5alpha-reductase inhibitors Drugs of today · 2004 · 7 citations
    17. Androgenetic alopecia - a literature review Journal of Education Health and Sport · 2025
    18. Characterization of response of murine hair follicle-derived keratinocyte against androgen and testosterone 5α-redactase activity Journal of dermatological science · 1994
    19. Faculty Opinions recommendation of Association between 5-alpha reductase inhibition and risk of hip fracture. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2008
    20. An overview on 5α-reductase inhibitors Steroids · 2009 · 219 citations
    21. The Risk of Venous Thromboembolism (VTE) in Men with Benign Prostatic Hyperplasia Treated with 5-Alpha Reductase Inhibitors (5ARIs). Clinical Epidemiology · 2021 · 6 citations
    22. The Dutasteride: Miraculous Drug in Alopecia Treatment A Review Zenodo (CERN European Organization for Nuclear Research) · 2023
    23. Androgen effects on the skin Cambridge University Press eBooks · 2015
    24. 5‐Alpha reductase inhibitors in androgenetic alopecia: Shifting paradigms, current concepts, comparative efficacy, and safety Dermatologic Therapy · 2020 · 19 citations
    25. Prostate cancer incidence among finasteride and alpha-blocker users in the Finnish Prostate Cancer Screening Trial British Journal of Cancer · 2009 · 49 citations
    26. Clinical relevance of testosterone and dihydrotestosterone metabolism in women ˜The œAmerican journal of medicine · 1995 · 31 citations
    27. Sexual Dysfunction Related to Drugs: a Critical Review. Part V: α-Blocker and 5-ARI Drugs Pharmacopsychiatry · 2015 · 15 citations
    28. Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function Current Urology Reports · 2014 · 11 citations
    29. Ciclosporin-Induced Generalised Hypertrichosis in a Transgender Woman Receiving Testosterone Blockers Cureus · 2026
    30. Do Alpha-Blockers and 5-Alpha Reductase Inhibitors Increase Dementia Risk? A Network Meta-analysis International Neurourology Journal · 2025