12 citations
,
October 1947 in “Journal of the Society of Dyers and Colourists” This study found that treatment with mercuric acetate modifies the elastic properties of Lincoln wool fibers more rapidly than human hair, explaining the enhanced unshrinkable quality of wool under certain conditions.
6 citations
,
August 2019 in “Indian drugs” This review discusses ethosomal delivery systems for topical drugs, highlighting their potential to improve treatment efficacy for conditions like herpes labialis and male pattern baldness, and reports no new clinical results.
2 citations
,
September 2022 in “Advances in Environmental Biology” This study found that ethanolic extracts of Avicennia marina leaves showed potential antibacterial activity against Vancomycin-Resistant Enterococcus faecium but were less effective than standard antibiotics.
1 citations
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September 2025 in “Plant Science Today” This study reported that an herbal formulation containing aqueous extracts of Hibiscus rosa sinensis and Vitex negundo demonstrated promising antimicrobial, antioxidant, anti-inflammatory, and cytotoxic activities, indicating potential health benefits and applications in managing autoimmune diseases.
1 citations
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January 2023 in “Journal of pharmaceutical and biological sciences” This review examines ethosomal structures and their mechanisms as skin delivery systems, outlining preparation methods and applications but presents no new experimental findings.
This study reported that hydrogels created from keratins extracted from human hair exhibit antibacterial properties and enhance tissue regeneration, suggesting their potential use in full-thickness skin repair, as demonstrated by increased collagen production and improved healing in vivo.
July 2024 in “International Journal of Advanced Research in Science Communication and Technology” This study explored the antibacterial and wound-healing effects of an 80% methanol extract from Hibiscus micranthus leaves, finding it effective against several bacterial strains and beneficial for wound healing in rats.
June 2021 in “International Journal of Biosciences (IJB)” This study reports that both aqueous and methanolic extracts of Tridax procumbens flowers demonstrated antibacterial activity against selected bacteria, indicating potential as antibacterial agents.
May 1962 in “Zhurnal Fizicheskoi Khimii (U.S.S.R.) For English translation see Russ. J. Phys. Chem. (Engl. Transl.)” This review discusses the complex pathophysiology of polycystic ovary syndrome and reports no clinical trial results, emphasizing the need for better understanding to improve treatment options.
119 citations
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December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.
99 citations
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June 2011 in “Journal of biomedical materials research. Part A” This study observed that keratose hydrogels sustained ciprofloxacin release over three weeks and inhibited Staphylococcus aureus growth in vitro for 23 days and in mice for 2 weeks.
55 citations
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June 2013 in “Dermatologic Surgery” This review discusses the use of ablative and nonablative fractional resurfacing for enhanced topical drug delivery in dermatology and reports no new clinical results; further studies are needed to explore these methods.
49 citations
,
September 2008 in “International journal of pharmaceutics” This study suggests that artificial sebum L may serve as an effective substitute for human sebum in drug transport studies, due to its similar physicochemical properties.
32 citations
,
February 1993 in “British Journal of Clinical Pharmacology” This study found that OPC-17116 can be reliably detected in hair, suggesting it can serve as an index of drug exposure and a time-marker in hair analysis.
29 citations
,
September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
29 citations
,
August 2005 in “Biopolymers” In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.
26 citations
,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.
21 citations
,
January 2012 in “Biological and Pharmaceutical Bulletin” This study found that using a combination of iontophoresis and liposomal delivery facilitated the effective intradermal administration of superoxide dismutase in rats, reducing oxidative skin damage from UV exposure.
21 citations
,
August 1991 in “The Journal of Dermatologic Surgery and Oncology” This study found that intraoperative tissue expansion increased the amount of excised scalp by 20-30% during scalp reduction surgery for male pattern alopecia.
13 citations
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June 2016 in “Dermatologic Therapy” This study found that minoxidil applied to a damp scalp may increase drug penetration in vitro, potentially improving treatment effectiveness.
12 citations
,
August 2012 in “ISRN Analytical Chemistry (Print)” This review discusses various chemical and instrumental methods for determining macrolides and reports no new experimental results.
11 citations
,
January 2000 in “Journal of cosmetic science” This study found that hydrolyzed wheat proteins extensively penetrated both untreated and chemically treated hair, primarily occupying areas like the endocuticle and cortex.
9 citations
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March 2018 in “Journal of the Formosan Medical Association” In this study, chitosan membranes enhanced melanocyte proliferation and survival by supporting both cell-cell and cell-substrate interactions, unlike polyvinyl alcohol membranes which only facilitated cell-cell interactions.
8 citations
,
August 2019 in “Journal of Drug Delivery and Therapeutics” This study aimed to formulate and evaluate a herbal gel containing Allium cepa extract for its physical properties, such as appearance, viscosity, and spreadability, but it does not report specific results or effectiveness in preventing hair loss.
7 citations
,
January 2020 in “Skin Pharmacology and Physiology” In this study using ex vivo porcine ear skin, researchers found that standard nail varnish applied gently creates effective follicular closures, preventing penetration of certain substances like fluorescein sodium salt and caffeine into hair follicles, whereas solvent-free varnish and rapid application techniques were less effective.
4 citations
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January 2010 in “International journal of trichology” Bexarotene gel shows promise as a new treatment for alopecia areata.
3 citations
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February 2023 in “Journal of drug delivery science and technology” In vitro, this study found that PTX and HU SF-FA NLCs showed greater cytotoxicity and apoptosis in ovarian cancer cells than pure paclitaxel, suggesting promise as a targeted drug delivery platform.
3 citations
,
October 2021 in “Journal of Cosmetic Dermatology” This study found that topical patches containing allicin from garlic extract may be a promising and cost-effective option for treating alopecia areata, offering better aesthetic acceptance than mashed garlic.
3 citations
,
October 2021 in “Clinica Chimica Acta” This study found that higher levels of dihydrotestosterone in the parietal region of the scalp may correlate with the clinical presentation of androgenetic alopecia.
3 citations
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September 2005 in “International Journal of Cosmetic Science” This study found that monounsaturated oils like olive oil penetrate hair fibers effectively, whereas polyunsaturated oils typically do not penetrate beyond the cuticle.