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Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Using neurohormones to control keratin can lead to new skin disease treatments.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Finasteride negatively affects fish reproduction and gonadal development.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.