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This study found that disrupting Sox21 in developing teeth leads to severe enamel hypoplasia, regional osteoporosis, and abnormal hair formation, with impaired dental epithelial differentiation and regulation of hair follicle cell fate.

A method was developed to grow hair follicles in a lab for research on hair growth and health.

This study notes the ongoing challenge in developing new drugs for androgenetic alopecia, mentioning that both minoxidil and finasteride were originally intended for treating hypertension. Results are not reported.

This study suggests that the MAEG protein may facilitate epithelial–mesenchymal interactions during hair follicle development by binding to RGD-binding integrins like α8β1.

This study found that disrupting the inturned gene in developing mouse epidermis halted hair follicle formation due to impaired keratinocyte differentiation, highlighting primary cilia's role in tissue-specific planar cell polarity signaling.

This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.

This article discusses the need for rational strategies in developing hair loss drugs targeting specific events in hair follicle cycling, reporting no clinical findings but emphasizing the importance of understanding molecular controls.

This report describes a rare case of alopecia areata universalis developing in a child during the recovery phase of phenobarbital-induced anti-convulsant hypersensitivity syndrome, which suggests a mechanism involving lymphocyte-related immune responses.

This review highlights the potential of 3D bioprinting in developing functional, patient-specific artificial skin, addressing limitations of traditional skin grafts and advancing regenerative medicine applications.

This study found that ING5 knockout mice are prone to developing lymphomas and severe dermatitis, suggesting ING5 plays a role in tumor suppression and stem cell maintenance in vivo.

This case series reports on three school-aged children developing alopecia areata shortly after COVID-19 infection, suggesting a potential association between the virus and this autoimmune hair loss condition.

This report describes a case of a man developing hair changes, including Beau's lines and Pohl-Pinkus constrictions, following ABVD chemotherapy.

This research overview provides insights into current in vitro models for drug testing in hair loss treatments, highlighting the limitations of traditional models and the progress in developing three-dimensional culture platforms for more effective screening of potential therapies.

People with celiac disease have a higher risk of developing alopecia areata.

Periodontitis may increase the risk of developing alopecia areata.

This study found that T cytokeratins appear more gradually and with complex coexpression patterns in developing nail structures compared to the more abrupt transition in hair follicles.

This study revealed that Patched receptors establish a Hedgehog signaling gradient in developing hair follicles, which may influence their formation and potentially offer a diagnostic tool for distinguishing Hedgehog-driven tumors.

This study used single-cell ATAC sequencing to map chromatin accessibility in developing mouse hair follicles, offering insights into the transcriptional regulation and epigenetic mechanisms underlying hair follicle development.

This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.

This review discusses the strategies and progress in developing bioengineered organ replacement therapies but reports no new clinical results, highlighting the potential for future regenerative solutions.

This manuscript reviews the potential of targeting the Wnt/β-catenin pathway for developing new treatments for androgenetic alopecia, providing insights but no clinical results.

This study found that mesenchymal cell processes from the dermal papilla contact epithelial hair matrix cells through gaps in the basal lamina during hair matrix cell differentiation in mouse vibrissa follicles.

This study found that modulating Wnt signaling can promote new hair follicle regeneration in adult mouse skin wounds, suggesting potential treatment strategies for scarring and alopecia.

This review examines the roles of macrophages and Langerhans cells in skin homeostasis and suggests that understanding these functions can aid in developing therapies for skin and hair regeneration, but it reports no new research findings.

This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.

This study developed a biomimetic 3-D co-culture system that enhances the hair-inductive properties of human dermal papilla cell aggregates, potentially improving hair follicle tissue engineering.

This study explores the regulatory effects of ursolic acid on macrophage function and suggests potential for developing new anti-inflammatory and immunomodulatory drugs, though further research is needed for clinical applications.

This study identifies macrophage-mediated immune signaling as a crucial factor in activating hair follicle stem cells and promoting hair regeneration, offering a new model for testing regenerative therapies for alopecia.

This study found that mice lacking both vitamin D and calcium-sensing receptors in epidermal keratinocytes are predisposed to developing squamous cell carcinoma as they age, due to impaired oxidative stress response and reduced DNA repair capabilities.

This study suggests that 70% ethanol extracts from certain medicinal plants may promote hair growth and be useful for developing hair care products.