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    Glossary Dermal Stem Cells

    specialized skin cells that regenerate and repair dermal tissue

    Dermal Stem Cells, also known as dermal progenitor cells, are specialized cells found in the skin's dermis layer that have the ability to self-renew and differentiate into various cell types, including fibroblasts, which are crucial for wound healing and collagen production. These cells play a significant role in skin regeneration and repair, making them a key focus in research on anti-aging treatments and therapies for skin-related conditions.

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    1. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009 · 330 citations
    2. Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages Experimental Dermatology · 2003 · 268 citations
    3. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014 · 184 citations
    4. Human dermal stem cells differentiate into functional epidermal melanocytes Journal of Cell Science · 2010 · 164 citations
    5. Comparative Characterization of Hair Follicle Dermal Stem Cells and Bone Marrow Mesenchymal Stem Cells Stem Cells and Development · 2006 · 151 citations
    6. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014 · 149 citations
    7. Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice Scientific Reports · 2017 · 113 citations
    8. Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog Genes & Development · 2016 · 75 citations
    9. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011 · 68 citations
    10. Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells Development · 1996 · 61 citations
    11. Modulation of Dermal Cell Activity During Hair Growth in the Rat Journal of Cutaneous Pathology · 1975 · 55 citations
    12. Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites Journal of Investigative Dermatology · 2013 · 51 citations
    13. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration Cell Reports · 2023 · 44 citations
    14. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Scientific Reports · 2017 · 42 citations
    15. Multifaceted role of hair follicle dermal cells in bioengineered skins 2016 · 33 citations
    16. Hair follicle reformation induced by dermal papilla cells from human scalp skin Archives of Dermatological Research · 2006 · 32 citations
    17. Rescuing key native traits in cultured dermal papilla cells for human hair regeneration Journal of Advanced Research · 2020 · 30 citations
    18. Dermal papilla cells induce keratinocyte tubulogenesis in culture Histochemistry and cell biology · 2010 · 28 citations
    19. Dermal-Epidermal Interactions--Follicle Derived Cell Populations in the Study of Hair-Growth Mechanisms. 1993 · 28 citations
    20. Microencapsulated human hair dermal papilla cells: a substitute for dermal papilla? Archives of Dermatological Research · 2008 · 25 citations
    21. Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system Journal of Tissue Engineering and Regenerative Medicine · 2015 · 23 citations
    22. Activating β-catenin signaling in CD133-positive dermal papilla cells increases hair inductivity FEBS Journal · 2016 · 23 citations
    23. Dermal-epidermal interactions—follicle-derived cell populations in the study of hair-growth mechanisms 1993 · 19 citations
    24. iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration PLOS ONE · 2016 · 19 citations
    25. Restoration of hair-inductive activity of cultured human follicular keratinocytes by co-culturing with dermal papilla cells Biochemical and Biophysical Research Communications · 2018 · 14 citations
    26. Human iPS Cell-Derived Cell Aggregates Exhibited Dermal Papilla Cell Properties in in vitro Three-Dimensional Assemblage Mimicking Hair Follicle Structures Frontiers in cell and developmental biology · 2021 · 10 citations
    27. Skin equivalent assay: An optimized method for testing for hair growth reconstitution capacity of epidermal and dermal cells Experimental Dermatology · 2019 · 8 citations
    28. Cryptomphalus aspersa Mollusc Egg Extract Promotes Regenerative Effects in Human Dermal Papilla Stem Cells International journal of molecular sciences · 2017 · 8 citations
    29. Effects of the biomimetic peptide Sh-Polypeptide 9 (CG-VEGF) on cocultures of human hair follicle dermal papilla cells and microvascular endothelial cells Experimental Dermatology · 2015 · 7 citations
    30. URB expression in human dermal papilla cells Journal of Dermatological Science · 2005 · 7 citations