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    Glossary Dehydroepiandrosterone

    hormone produced by adrenal glands, precursor to sex hormones

    Dehydroepiandrosterone (DHEA) is a hormone produced by the adrenal glands, which are located above the kidneys. It serves as a precursor to male and female sex hormones, including testosterone and estrogen. DHEA levels naturally decline with age and are sometimes supplemented to address various health issues, such as adrenal insufficiency, depression, and certain autoimmune diseases.

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    1. Endocrine and Intracrine Sources of Androgens in Women: Inhibition of Breast Cancer and Other Roles of Androgens and Their Precursor Dehydroepiandrosterone Endocrine Reviews · 2003 · 515 citations
    2. Is dehydroepiandrosterone a hormone? Journal of Endocrinology · 2005 · 403 citations
    3. The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors Drug Metabolism Reviews · 2006 · 219 citations
    4. Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone Journal of Investigative Dermatology · 2005 · 168 citations
    5. Puberty in Boys: Correlation of Plasma Levels of Gonadotropins (LH, FSH), Androgens (Testosterone, Androstenedione, Dehydroepiandrosterone and Its Sulfate), Estrogens (Estrone and Estradiol) and Progestins (Progesterone and 17-Hydroxyprogesterone) The Journal of Clinical Endocrinology & Metabolism · 1975 · 96 citations
    6. ADRENOCORTICAL FUNCTION IN PUBERTY Serum ACTH, Cortisol and Dehydroepiandrosterone in Girls and Boys Acta Paediatrica · 1979 · 95 citations
    7. Serum elevation of dehydroepiandrosterone sulfate associated with male pattern baldness in young men Journal of the American Academy of Dermatology · 1987 · 52 citations
    8. Effects of Dehydroepiandrosterone Therapy on Pubic Hair Growth and Psychological Well-Being in Adolescent Girls and Young Women with Central Adrenal Insufficiency: A Double-Blind, Randomized, Placebo-Controlled Phase III Trial The Journal of Clinical Endocrinology & Metabolism · 2009 · 49 citations
    9. Mechanisms of Action of Dehydroepiandrosterone Vitamins and hormones · 2018 · 35 citations
    10. The Metabolism of Dehydroepiandrosterone by Human Scalp Hair Follicles The Journal of Clinical Endocrinology & Metabolism · 1973 · 28 citations
    11. Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats European Journal of Pharmacology · 2007 · 27 citations
    12. Elevated Dehydroepiandrosterone Sulfate Levels as the Reproductive Phenotype in the Brothers of Women with Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2002 · 27 citations
    13. Dehydroepiandrosterone for women in the peri- or postmenopausal phase The Cochrane library · 2015 · 22 citations
    14. Serum prolactin and dehydroepiandrosterone concentrations during the summer and winter hair growth cycles of mink (Mustela vison) Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 1998 · 18 citations
    15. Treatment of androgenic disorders with dexamethasone: Dose-response relationship for suppression of dehydroepiandrosterone sulfate Journal of The American Academy of Dermatology · 1990 · 18 citations
    16. New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors Steroids · 2011 · 14 citations
    17. Within-person changes of cortisol, dehydroepiandrosterone, testosterone, estradiol, and progesterone in hair across pregnancy, with comparison to a non-pregnant reference group Comprehensive psychoneuroendocrinology · 2020 · 12 citations
    18. Dehydroepiandrosterone (DHEA) and Testosterone Concentrations in Human Hair after Chronic DHEA Supplementation Clinical Chemistry · 2000 · 12 citations
    19. Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin Journal of Endocrinology · 2000 · 11 citations
    20. Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles British Journal of Dermatology · 1979 · 11 citations
    21. Measurement of cortisol, dehydroepiandrosterone, and testosterone in the hair of children: Preliminary results and promising indications Developmental Psychobiology · 2018 · 10 citations
    22. <i>In vitro</i>metabolism of dehydroepiandrosterone and testosterone by canine hair follicle cells Veterinary Dermatology · 2004 · 9 citations
    23. METABOLISM OF DEHYDROEPIANDROSTERONE BY ISOLATED HUMAN HAIR FOLLICLES European Journal of Endocrinology · 1971 · 7 citations
    24. Dehydroepiandrosterone- and glucose-6-phosphate-dehydrogenases in the hair cycle of the rat Archives of Dermatological Research · 1971 · 7 citations
    25. Role of Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate for the Maintenance of Axillary Hair in Women Hormone and Metabolic Research · 1993 · 5 citations
    26. Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate (DHEA-S) in the majority of the alopecia areata patients: Is it a primitive and pathogenic perturbation of hypothalamic-pituitary-adrenal axis? International journal of trichology · 2011 · 3 citations
    27. Testosterone, sex hormone-binding globulin and dehydroepiandrosterone levels and cervical length of Egyptian women with a history of recurrent miscarriages, polycystic ovary syndrome and without the conditions at three stages of pregnancy Journal of Obstetrics and Gynaecology · 2023 · 1 citations
    28. Anti-SARS-CoV-2 Action of 5α-Reductase Inhibitors May Be Mediated by Dehydroepiandrosterone. Letter. The Journal of Urology · 2022 · 1 citations
    29. Local stimulation of sebaceous gland activity by the topical administration of dehydroepiandrosterone 1988 · 1 citations
    30. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone sulfate in human serum and plasma Clinical Chemistry and Laboratory Medicine (CCLM) · 2025 · 1 citations