30 citations,
July 2009 in “Experimental and clinical endocrinology & diabetes” Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
30 citations,
January 1998 in “Dermatology” Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.
26 citations,
December 1981 in “British journal of dermatology/British journal of dermatology, Supplement” Cyproterone acetate reduced hair growth in most hirsute females and made hair softer, thinner, and lighter.
23 citations,
April 1999 in “The Journal of Clinical Endocrinology and Metabolism” All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.
20 citations,
July 1990 in “Clinical and experimental dermatology” Taking cyproterone acetate and ethinyl oestradiol for hair loss can lower vitamin B12 levels in women.
18 citations,
January 1996 in “Gynecologic and obstetric investigation” The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.
18 citations,
August 1985 in “European journal of endocrinology” Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.
18 citations,
September 1979 in “DMW - Deutsche Medizinische Wochenschrift” Diane is effective for treating acne, seborrhoea, androgenic alopecia, and mild hirsutism in women.
16 citations,
January 1989 in “Springer eBooks” Cyproterone acetate effectively treats female hair loss by increasing healthy hair and decreasing unhealthy hair, but doesn't change hair thickness.
15 citations,
June 2011 in “British Journal of Dermatology” No link found between aromatase gene and female hair loss.
15 citations,
November 1983 in “British journal of dermatology/British journal of dermatology, Supplement” Testosterone increases hamster hair growth; cyproterone acetate reduces it.
14 citations,
January 2013 in “Hormone and Metabolic Research” The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.
14 citations,
January 1980 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Both treatments reduced androgen levels and hair growth in women with hirsutism.
13 citations,
January 2013 in “Applied and Environmental Microbiology” A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.
13 citations,
January 2014 in “Aesthetic Surgery Journal” Cyperus rotundus oil effectively reduces unwanted hair without side effects.
12 citations,
August 2017 in “Pharmaceutical medicine” Most doctors know the thrombosis risk with Cyproterone/Ethinylestradiol, but some lack details on less common risks and patient instructions; educational materials are underused but useful.
12 citations,
October 1988 in “Clinics in dermatology” The mouse model could be useful for baldness research and testing treatments like testosterone, cyproterone acetate, and minoxidil.
11 citations,
April 2017 in “The European Journal of Contraception & Reproductive Health Care” Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.
11 citations,
January 2017 in “Biochemical and biophysical research communications” 1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.
10 citations,
December 2002 in “International Journal of Dermatology” Cyproterone acetate can cause rare shortness of breath in women.
9 citations,
February 2013 in “Hormone and Metabolic Research” Mutations in the CYP21A2 gene are not a major factor in causing PCOS.
9 citations,
December 1987 in “European journal of endocrinology” The treatment significantly reduced hair growth and male hormone levels in hirsute women.
8 citations,
April 1991 in “European journal of endocrinology” 3α-AdiolG is a good marker for androgen activity in women with excessive hair growth and decreases with anti-androgen treatment.
8 citations,
April 1990 in “Hormone and Metabolic Research” The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.
8 citations,
November 1978 in “British journal of dermatology/British journal of dermatology, Supplement” Cyproterone acetate can effectively treat idiopathic hirsutism, but ethinyl oestradiol and lynoestrenol may not always reduce hair growth.
7 citations,
January 2019 in “Australasian Journal of Dermatology” A genetic marker linked to a type of hair loss was found in most patients studied.
7 citations,
August 2019 in “Journal of Ovarian Research” Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.
7 citations,
January 2015 in “Dermatology” Two gene variations, rs6493497 and rs7176005, may be linked to female hair loss in Chinese people.
6 citations,
October 2016 in “Contraception” The medication cyproterone acetate/ethinylestradiol is usually prescribed correctly for acne after other treatments don't work.
5 citations,
June 2021 in “Journal of neurology, neurosurgery and psychiatry” Taking high doses of Cyproterone acetate significantly increases the risk of meningioma in females.