January 2024 in “Indian Journal of Pharmaceutical Sciences” This study hypothesizes that the curling of hair may result from the contraction of the Arrector Pili Muscle, contributing to the diverse types of curly hair.
January 2024 in “Indian Journal of Pharmaceutical Sciences” This study hypothesizes that curly hair is shaped by the contraction of the Arrector Pili Muscle within the follicle, potentially modifiable through muscle-relaxing treatments, but further research is needed to confirm this mechanism.
January 2024 in “World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany” Polisorbate 20 is not suitable for curl creams due to instability.
December 2023 in “Data in Brief” In this study, the researchers conducted tensile tests on individual curly human hair fibers sourced from a female donor and found distinct mechanical properties under various conditions, including different strain rates and temperatures, both dry and in saline immersion.
May 2023 in “Accounts of chemical research” This study aimed to identify new quantitative geometric and mechanical parameters for curly and kinky hair using various microscopy and mechanical analysis methods, revealing correlations between hair fiber geometry and mechanical performance to enhance personal care product development and promote cultural inclusion.
February 2019 in “IP Indian journal of clinical and experimental dermatology” In this study, continuous use of chemical hair relaxers and curlers was associated with adverse effects such as hair fall, thinning, and scalp irritation in patients with telogen effluvium.
January 2019 in “Pediatric Oncall” This article reviews the use of valproate in epilepsy treatment and its side effects, noting that hair texture changes such as curly hair are a rarely reported effect, but reports no new clinical results.
March 2018 in “Journal of Experimental Biology” This study found that the curl in hair is due to the arrangement of different cell types, with shorter paracortical cells inside the curve and longer orthocortical cells outside.
This study mapped the curly mutation in mice to a specific region on chromosome 11, identifying it as a candidate model for studying human genetic hair disorders.
January 2006 in “Seibutsu Butsuri” Curly and straight hair differ in how their internal fibers are arranged.
16 citations
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June 2017 in “PLoS ONE” This small study reports that a 6-group geometric classification method is more reliable for classifying human hair curl, although a digital system could further reduce errors.
95 citations
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October 2007 in “International Journal of Dermatology” This study found that human hair can be classified into eight main types based on objective measurements of shape, rather than ethnic categories, enhancing the understanding of hair diversity globally.
19 citations
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October 2016 in “Journal of oncology pharmacy practice” In this study, the first case of a persistent curly hair phenotype was reported with nivolumab treatment in a patient with metastatic squamous cell lung cancer.
17 citations
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November 2013 in “Clinical and experimental dermatology” This case report describes repigmentation and curling of hair in a patient undergoing acitretin therapy.
14 citations
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January 2006 in “Skinmed” A woman developed white patches on her skin and curly hair after hepatitis C treatment, likely due to the medication interferon alpha.
1 citations
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October 2019 in “Epileptic disorders” In this case report, a 13-year-old girl with Pitt-Hopkins syndrome developed hair curling after starting the antiepileptic drug perampanel, which had not been previously reported as a side effect.
July 2026 in “Open Minds International Journal” This review suggests that multifunctional cosmetic systems, particularly HIVEN Curl Code ®, may help control frizz and maintain curl definition in highly curly hair by utilizing various conditioning and biofunctional ingredients.
April 2026 in “Journal of Cosmetic Dermatology” This study reports that specific hair care practices common among individuals with high-curl-pattern hair could exacerbate seborrheic dermatitis, presenting significant treatment challenges and psychological impacts, and emphasizes the need for further research to tailor culturally sensitive solutions.
1 citations
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March 2023 in “Journal of Natural Fibers” This study explored using tyrosine as a cross-linking agent for curling Asian hair and found that it could shape hair effectively before washing without damaging the fibers, though the method was less effective after washing compared to commercial products.
April 2018 in “Pharmaceutical and biological evaluations” This review discusses polycystic ovarian syndrome, highlighting its symptoms, potential causes, and treatment options, but reports no new clinical results.
January 1993 in “Inpharma Weekly” A new food supplement was highly effective in curing hair loss in young men.
65 citations
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March 2017 in “Experimental Dermatology” This review discusses the genetic and biological factors influencing hair curliness, revealing strong links to specific protein variations, and reports no new clinical results.
39 citations
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January 2020 in “Frontiers in Genetics” This study found that stage-specific epigenetic changes, particularly involving the gene PDGFC, may affect wool fiber development in Zhongwei goats, potentially serving as a biomarker for fur goat selection.
This paper explores the diverse patterns and social significance of Black hair, approaching it as an art form, mathematical pattern, and ethnomathematic entity, and seeks to dispel myths while highlighting its vast possibilities.
55 citations
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August 2013 in “PloS one” This study suggests that changes in expressed transcripts and splice isoforms may explain the transition from curly to straight fleece in Chinese Tan sheep as they age.
13 citations
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November 2018 in “Animal Genetics” This study suggests that a newly identified KRT 71 gene variant may be responsible for curly hair in Curly Coated Retrievers and potentially contributes to follicular dysplasia.
5 citations
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November 2012 in “Journal of the American Academy of Dermatology” This case report describes a 3-year-old girl with short hair since birth, showing normal hair density with many vellus and intermediate hairs, and no hair shaft abnormalities.
June 2023 in “Frontiers in Genetics” This study suggests that the curly hair phenotype in Mangalitza pigs may involve complex gene interactions related to calcium signaling and lipid metabolism, rather than changes in TRPM2 or CYP4F3 expression.
July 2025 in “Case Reports in Dermatology” This case report highlights that early signs like pili torti may precede lichen planopilaris in some patients, emphasizing the importance of timely intervention to prevent permanent hair loss.
17 citations
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May 2018 in “BMC genomics” This study found that miR-432 inhibits KRT83 expression, revealing potential molecular mechanisms for the formation of curly fleece in Tan sheep and suggesting implications for understanding curly hair formation in humans.