13 citations
,
April 2018 in “Scientific Reports” In this study, genetic variants in the KRT25 and SP6 genes were found to be responsible for curly hair in horses, with the KRT25 variant also causing hypotrichosis due to an epistatic effect.
2 citations
,
July 2013 in “Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista)” This study found that the shampoo formulation with Polyurethane-14 and AMP-acrylates copolymer improved curl definition and reduced frizz and volume in natural and curly hair tresses compared to the control.
September 2025 in “Cosmetics” In this study, researchers found that the lipid composition in hair significantly affects water diffusion and may explain differences in dyeing and cosmetic treatment responses between Asian and European hair, with CP2 fibers having more lipids than CP3 fibers.
This study identified new geometric and mechanical parameters for curly and kinky/coily hair, which may inform more effective personal care products tailored to these hair types.
This study used quantitative methods to identify new geometric and mechanical parameters of curly and kinky/coily hair, aiming to improve classification and develop better personal care products for these hair types.
September 2015 in “The European physical journal. E, Soft matter and biological physics/The European physical journal. E, Soft matter” In this study, a mechanical model was developed to describe and validate the effectiveness of overnight hair curling, suggesting that combining it with hair fixatives can maintain a desired curl for over a day.
January 2007 in “Proceedings of the Korean Fiber Society Conference” New resin B makes artificial hair fibers hold curls longer than traditional resin A.
578 citations
,
April 1993 in “Cell” This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.
78 citations
,
June 2003 in “Journal of the American Academy of Dermatology” This article reviews the autonomous functioning and complex interactions within hair follicles, emphasizing their unique composition and differentiation pathways, but does not report new research findings.
40 citations
,
June 2013 in “Scientific Reports” This study found an association between a splice site variant in the KRT71 gene and curly hair in Selkirk Rex cats, identifying a significant locus on chromosome B4.
35 citations
,
September 2003 in “Archives of dermatology” This study proposed that the tiger tail phenomenon in trichothiodystrophy hair is caused by regular undulations of hair fibers, altering the optical properties seen under polarized light.
29 citations
,
January 2003 in “Genomics” A new mouse mutation causes skin and hair issues, influenced by another gene.
18 citations
,
February 2001 in “Der Hautarzt” This case study of a 50-year-old woman with myotonic dystrophy and multiple basal cell carcinomas suggests there could be a genetic predisposition for certain cutaneous tumors in such patients.
13 citations
,
March 2017 in “Skin Research and Technology” In this study, formaldehyde hair straighteners significantly damaged curly hair by reducing break stress and break extension, while glyoxylic acid had a milder effect; both treatments increased shear modulus and decreased water sorption.
13 citations
,
November 2012 in “International Journal of Dermatology” This study of African-American women found that those perceiving greater hair breakage showed lower break stress and higher premature failure rates, linked to grooming practices and hair curvature.
12 citations
,
July 2015 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that mechanical damage from grooming and environmental factors contributes to crack formation and eventual breakage in African-American hair, highlighting the need for continuous care.
8 citations
,
December 2020 in “Scientific reports” This study examined the genetic basis for the curly hair trait in Mangalitza pigs, finding two specific genetic variants that contribute to this distinctive phenotype through autosomal dominant inheritance.
8 citations
,
July 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the tensile strength of curly hair is influenced by two main components, with springiness (toe region) contributing significantly, unlike in noncurly hair where it is negligible.
8 citations
,
March 2014 in “Dermatologic Clinics” This article discusses surgical hair restoration for individuals with curly hair, emphasizing specific considerations and techniques required, but reports no new clinical results.
6 citations
,
October 2018 in “Drug safety - case reports” In this report, two women treated with alitretinoin experienced persistent curling of their previously straight hair, suggesting a likely causal link between the medication and hair texture changes.
In this study conducted at Shafa Hospital, Kerman, Iran, 3.5% of patients using sodium valproate as an antiepileptic experienced hair loss and curling over ten years.
6 citations
,
March 1986 in “PubMed” This case study describes a 19-year-old female patient who gained 13 kg and experienced hair changes while on valproic acid, and partially lost weight after reducing the dosage, but hair changes persisted.
5 citations
,
January 2016 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” This report discusses that curly hair is a very rare side effect of valproate, a medication used as a mood stabilizer for bipolar disorder, though such drug-induced hair changes are uncommon.
3 citations
,
November 2019 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” Valproate can cause both hair loss and curly hair in bipolar disorder patients.
1 citations
,
July 2024 in “International Journal of Cosmetic Science” This study validated a new tool for assessing curly hair manageability, finding that hair curvature is a key factor influencing hair practices and product attitudes among women with natural curly hair.
1 citations
,
March 2023 in “Frontiers in Cardiovascular Medicine” A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.
1 citations
,
April 2022 in “International Journal of Women's Dermatology” This study suggests that curl pattern classification could help improve patient communication and risk stratification in hair loss disorders, but its clinical utility in dermatology needs further validation.
January 2026 in “Biomedical and Biopharmaceutical Research” This study found that formulations containing pequi and buriti oils improved texture properties and significantly increased gloss in curly hair, with pequi oil also significantly enhancing tensile strength.
November 2024 in “Journal of Microscopy” This study found that micro-computed tomography (micro-CT) was highly effective for analyzing the cross-sectional geometry of hair fibres, including the medulla in highly curled hair, but less effective than scanning electron microscopy for surface details.
In this research, the author hypothesizes that curly hair is influenced by the contraction of the Arrector Pili muscle, suggesting that its relaxation through specific treatments could potentially modulate hair follicle curvature, but further studies are needed to confirm this mechanism.