5 citations
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December 2016 in “Microscopy Research and Technique” This study suggests that prenatal infusion of epidermal neural crest stem cells may improve certain neural markers and reduce cortical injury in a mouse model of methylazoxymethanol-induced malformations.
4 citations
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February 2023 in “International Journal of Stem Cells” The FTO gene hinders stem cells in hair follicles from becoming pigment cells.
3 citations
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May 2008 in “Journal of Visualized Experiments” This video provides a step-by-step protocol for isolating and cultivating multipotent EPI-NCSC from mouse whisker follicles for research on cell differentiation.
2 citations
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April 2014 in “PubMed” This rat study found that a PLGA conduit filled with neural crest stem cells derived from hair follicles showed promising results in repairing peripheral nerve injuries, partially restoring sensory function and improving nerve structure.
1 citations
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August 2024 in “Heliyon” This study reports that hair follicle neural crest stem cells in mice can be differentiated into melanocytes, potentially aiding repigmentation in vitiligo-affected areas.
1 citations
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July 2020 in “Revista Cereus” This study highlights microneedling as a safe and effective technique for treating androgenetic alopecia in men by permeating active agents, stimulating collagen, and enhancing angiogenesis, which may improve hair growth by activating cellular division and growth.
August 2026 in “Mendeley Data” In this study, researchers explored how hair follicle neural crest stem cell-derived exosomes, particularly those carrying miR-214-3p, promote neurite outgrowth and aid peripheral nerve regeneration, supported by detailed in vitro and in vivo data on nerve repair and functional recovery in rat models.
August 2026 in “Mendeley Data” This review article systematically summarizes current knowledge on using hair follicle neural crest stem cells and their exosomes for repairing peripheral nerve injuries, focusing on the molecular mechanisms and potential applications. The dataset includes comparison tables and diagrams to visually present findings from existing research.
August 2026 in “Mendeley Data” This review systematically assembles recent insights into the use of hair follicle neural crest stem cells and their exosomes for peripheral nerve injury repair, highlighting molecular mechanisms and possible translational applications, with comprehensive tables and diagrams summarizing existing literature.
May 2026 in “Mendeley Data” In this review, the authors systematically summarize recent advances in using hair follicle neural crest stem cells and their exosomes for repairing peripheral nerve injuries, focusing on mechanisms and applications derived from existing literature, although it does not include primary experimental data.
January 2026 in “Magazine Portal Bibliotech Digital (Universidad Nacional de Colombia)” This study found that rosemary extracts, both individually and in combination as shampoo and hair tonic, stimulated significant hair growth in male C57BL6//BIOU mice, even surpassing the growth achieved with the commercial drug 5% minoxidil.
January 2026 in “Mendeley Data” This dataset supports a study suggesting that hair follicle neural crest stem cell-derived exosomes carrying miR-214-3p may promote neurite outgrowth and aid peripheral nerve regeneration in vitro and in vivo.
January 2026 in “Mendeley Data” This study's dataset provides summary figures and tables reviewing recent advances in using hair follicle neural crest stem cells and their exosomes for repairing peripheral nerve injuries, focusing on their molecular mechanisms and potential clinical applications.
February 2025 in “FASEB BioAdvances” In this study, hypoxic conditions were found to enhance stemness in hair follicle neural crest stem cells, while inhibiting the Hippo pathway significantly decreased their proliferation.
This study found that exosomes derived from hair follicle neural crest stem cells significantly promoted nerve regeneration in injured neurons, particularly when overexpressing miR-214-3p, which enhanced axon extension and motor function recovery in both in vitro and in vivo models.
November 2023 in “Research Square (Research Square)” In this study, researchers used NIR-II fluorescence imaging to track the survival and migration of EPI-NCSCs in rat models, finding that these stem cells aided in repairing facial nerve defects when applied via acellular nerve allografts.
In this randomized clinical trial, the use of Cellcurin serum for 12 weeks was associated with a significant increase in hair density and terminal hair thickness in individuals with androgenetic alopecia.
February 2020 in “Journal of chemical neuroanatomy” This study suggests that five small molecules can induce hair follicle neural crest stem cells to differentiate toward motor neuron progenitor cells with a unipotent differentiation potential.
December 2022 in “Stem Cells and Development” The researchers reported that using exosomes from hair follicle stem cells with acellular nerve allografts helped bridge facial nerve defects in rats and may match the effectiveness of autograft therapy.
37 citations
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May 2018 in “Developmental Biology” This review discusses the role of neural crest stem cell-like states in adult neural crest-derived tissues, suggesting they may contribute to tissue repair by generating new cell types and activating repair programs.
June 2026 in “RCMOS - Revista Científica Multidisciplinar O Saber” This descriptive literature review suggests that rosemary essential oil may stimulate hair growth in androgenetic alopecia with effects similar to 2% minoxidil, yet highlights the need for more robust clinical trials to confirm these findings and assess complementary methods like scalp massage and high-frequency treatment.
November 2025 in “Aurum Revista Multidisciplinar” This study found that microneedling combined with growth factors significantly improved blood circulation, hair thickness, strand resistance, and psychological well-being in patients with androgenetic alopecia, suggesting this combination as a promising and safe treatment option.
January 2022 in “Revista Saúde em Foco” This review suggests that combining microneedling with growth factors may significantly stimulate eyebrow growth by promoting new hair follicle formation and improving cellular processes.
March 2013 in “Revista Brasileira de Cirurgia Plástica” This article reviews advances in hair transplant techniques such as megasessions of micro and mini grafts, highlighting platelet growth factors' potential to enhance hair density, without reporting new clinical findings.
2 citations
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July 2022 in “Frontiers in Veterinary Science” This case report describes a rare instance of a Chinese Crested dog with leukocyte chimerism, normal female external genitalia, and hormonally active Sertoli cell tumors, demonstrating surgery as a curative treatment option.
2 citations
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January 2022 in “Journal of Oleo Science” This study found that oil from CG17 garden cress seeds had higher amounts of β-carotenoids, tocopherols, and vitamins compared to other genotypes, with varying physiochemical properties across all seeds.
January 2025 in “Surgical & Cosmetic Dermatology” In this animal study, a topical gel containing ethyl-methyl-hydroxypyridine succinate showed potential in accelerating hair regrowth and improving skin biochemical parameters in rats with chemically induced alopecia, suggesting its possible benefit for alopecia related to oxidative stress.
This review discusses the potential effectiveness of certain essential oils in promoting hair growth for alopecia and reports no new clinical trials; the authors suggest these oils may increase hair thickness and volume.
12 citations
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July 2019 in “Veterinary Dermatology” The study suggests that nestin-expressing progenitor cells can differentiate into outer root sheath keratinocytes in hair follicles, indicating distinct progenitors for different hair follicle and epidermal components.