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This study introduced a validated LC-MS/MS-based method for profiling long-term steroid concentrations in human scalp hair, offering potential applications in endocrinology research.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

This study describes the first case of female pseudohermaphroditism due to a novel homozygous glucocorticoid receptor gene mutation, indicating possible pre- and postnatal virilization in affected females.

This study found that pubic skin fibroblasts respond to androgens, increasing 5α-reductase activity via an androgen receptor-mediated mechanism, suggesting its potential as a marker of androgen action in vitro.

In this study, ketoconazole treatment improved acne in all women and reduced hirsutism in some, but it caused several side effects and requires careful monitoring.

In this case study, a 55-year-old woman with androgenetic alopecia was ultimately diagnosed with hepatic cortisone reductase deficiency after initially suspected 21-hydroxylase deficiency was ruled out.

This study describes molecular mechanisms explaining how sex and stress steroids rapidly modulate dendritic spine formation in hippocampal neurons, suggesting recovery-like effects under steroid-depleted conditions compared to intact conditions.

This study suggests that many men with premature balding exhibit a hormonal pattern similar to some aspects of polycystic ovary syndrome in women.

This review discusses the evaluation, clinical presentation, and cutaneous manifestations of congenital adrenal hyperplasia, focusing on differential diagnosis challenges with polycystic ovary syndrome, and reports no new clinical findings.

This study found that women with acne resistant to conventional treatments had significantly higher levels of testosterone, DHEA‑S, prolactin, and LH, suggesting potential underlying hormonal disorders.

This review discusses the clinical features, genetics, and treatment of 21-hydroxylase deficiency, a common type of congenital adrenal hyperplasia, and reports no new research findings.

In this study, women with androgenic alopecia showed increased excretion of steroid metabolites and heightened 5α-reductase activity, suggesting these may contribute to the condition's hormonal abnormalities.

This study found that men with androgenic alopecia had significantly higher levels of certain urinary steroid metabolites, suggesting increased 5 alpha-reductase activity and possible mild hyperadrenal activity.

In this study, low-dose spironolactone effectively reduced hirsutism in women and stopped hair loss in one woman with alopecia areata, without significant side effects over 12 menstrual cycles.

This study used a glucocorticoid-injection model to mimic kidney-yang deficiency syndrome and reported symptoms related to hormonal imbalances in the hypothalamic-pituitary-target gland axes.

This study found that in female patients with androgenic hair loss and hirsutism, complex hormonal disturbances include elevated cortisol and thyroid hormone imbalances, rather than elevated androgen levels alone.

This review discusses the roles of steroid hormone receptors in lung function related to COVID-19 and outlines ongoing clinical trials of steroid receptor ligands, but reports no new results.

This study found that cortisol and corticosterone led to thinning of the epidermis and hair follicle regression in fetal mouse skin, while testosterone promoted differentiation and sebaceous gland development.

This review discusses imaging's role in the diagnosis and management of congenital adrenal hyperplasia and reports no new clinical results; it suggests a potential presentation route via incidental radiologic findings.

This study found that higher levels of dihydrotestosterone in the parietal region of the scalp may correlate with the clinical presentation of androgenetic alopecia.

This case report details a 26-year-old woman with a rare large functional adrenal myelolipoma, characterized by elevated hormone levels and requiring surgical intervention.

This study developed a method to measure local steroid hormone concentrations in hair, providing new insights into hormone dynamics associated with androgenetic alopecia.

This case study suggests that long-term treatment with buprenorphine/naloxone for opioid addiction may lead to secondary adrenal insufficiency, warranting further investigation.

This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

This article discusses the complexities of diagnosing pituitary dependent hyperadrenocorticism in dogs and reports no new clinical findings, highlighting issues with varied symptoms and episodic hormone secretion complicating diagnosis.

This study evaluated factors influencing hair steroid concentrations in early infancy, finding small effects from birth mode, season, and age-related changes, suggesting hair analysis as promising for assessing long-term endocrine activity.

This study developed a sensitive method for analyzing nine biomarkers in hair, revealing an association between chronic tobacco smoke exposure and stress, highlighting its potential use in understanding the relationship between long-term tobacco exposure and chronic stress.

In a clinical case study, researchers identified adrenocortical adenoma as the cause of hyperandrogenism syndrome in a preschool-aged girl, following a comprehensive diagnostic process and successful surgical intervention to remove the tumor, leading to positive clinical improvements.

Skin hormone levels change significantly after menopause.