In this study, researchers found that cosmetic formulations containing guaraná extract effectively controlled oiliness in oily skin and hair by reducing sebaceous gland activity and lipid content without compromising skin barrier function, making them promising for managing excessive sebum production.
2 citations
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August 2016 in “Journal of Investigative Dermatology”
September 2022 in “KnE medicine” In this study, variations in candle nut oil concentration (5%, 6%, 7%) impacted the characteristics and stability of a hair tonic nanoemulsion, influencing factors like droplet size, pH, and viscosity.
March 2024 in “Korean Journal of Pharmacognosy” This study found that Nymphaea caerulea flower extract may improve scalp condition by reducing sebum production, inhibiting inflammation and microbial factors, and decreasing cortisol and vascular permeability.
January 2022 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” In this study, the application of Enriched and Enhanced Virgin Coconut Oil reportedly improved hair growth and reduced the appearance of scars in a teacher with cancer, suggesting benefits over typical post-chemotherapy recovery.
39 citations
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December 2013 in “Phytotherapy Research” This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.
October 2024 in “Jurnal Pharmascience” This study concluded that formulations of celery and candlenut extracts meet the necessary criteria for use as a spray preparation aimed at promoting hair growth, based on evaluations of physical properties and consistency.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This literature review suggests that Cyperus rotundus L extract shows promise as a natural hair growth agent due to its bioactive compounds and mechanisms that stimulate hair growth, although more human clinical trials are needed to confirm its safety and efficacy.
August 2026 in “Genetics and Molecular Research” This study found that hydroalcoholic extracts of Trigonella foenum-graecum L. seeds were rich in bioactive phytochemicals and demonstrated potential therapeutic properties against dandruff, alopecia, and oxidative stress through molecular docking analysis of key constituents such as diosgenin, kaempferol, and quercetin.
16 citations
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June 2019 in “Industrial Biotechnology” In this study, researchers found that the conventional solvent extraction method yielded the highest polyphenol content and antioxidant activity from Ascophyllum nodosum seaweed on Québec's North Shore.
May 2026 in “International Journal of Applied Pharmaceutics” This study developed a stable nanoemulsion of Avicennia marina heartwood extract showing promising anti-dandruff activity against Pityrosporum ovale and favorable physicochemical properties, which supports its potential use in topical formulations.
2 citations
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January 2020 in “BioMed Research International” This study found that Phaeodactylum tricornutum extract enhanced hair follicle cell proliferation, indicated by increased keratin and ERK1/2 signaling, suggesting its potential for hair care applications.
1 citations
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December 2014 in “International Journal of Pharmacy and Pharmaceutical Sciences” The study observed that Carthamus tinctorius extract-loaded lipid carriers promoted hair growth in C57BL/6 mice more effectively than minoxidil, although further research on humans is needed for confirmation.
6 citations
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October 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” This study found that rice bran ash extract enhanced melanin biosynthesis-related protein expression in a 3D hair follicle-like tissue model and hair follicle organ culture, suggesting potential for future research in melanogenesis.
This literature review suggests that Cyperus rotundus L extract is a promising natural agent for promoting hair growth due to its bioactive compounds and mechanisms of action, but emphasizes the need for further human clinical trials to confirm its safety and effectiveness.
4 citations
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July 2023 in “Legume Research - An International Journal” This review integrated findings on the nutritional, pharmacological, and techno-functional properties of Leucaena seeds, highlighting their potential benefits and challenges for human nutrition, particularly due to the presence of the antinutrient mimosine, which can cause adverse effects.
14 citations
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July 2021 in “Biomolecules” This study found that Centipeda minima extract promotes hair growth by activating Wnt/β-catenin, ERK, and JNK signaling pathways in human hair follicle dermal papilla cells.
21 citations
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February 2023 in “Pharmaceuticals” This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.
13 citations
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February 2019 in “Journal of Microencapsulation” This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.
20 citations
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February 2018 in “Cell transplantation” This study found that the water extract of Cinnamomum osmophloeum Kanehira leaves enhanced hair growth in vitro and in a mouse model, suggesting potential use for treating hair loss.
December 2025 in “Asian Journal of Beauty and Cosmetology” This study found that applying soybean oil extract to damaged hair significantly improved brightness, tensile strength, absorbance, and gloss, suggesting its potential in enhancing hair condition. Further research is needed to explore how different natural extracts affect damaged hair.
5 citations
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January 2018 in “Thai Journal of Pharmaceutical Sciences (TJPS)” This study found that extracts from riceberry broken rice and crude riceberry rice oil contain bioactive compounds with antioxidant and tyrosinase-stimulating activities, suggesting potential use in hair product development.
December 2024 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case report describes a 62-year-old female patient with onycholysis whose condition recurred despite taking Coix seed extract, although both initial and recurrent symptoms resolved with its use, suggesting limited efficacy and warranting further study.
37 citations
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January 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.
1 citations
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August 2024 in “Polymers” This study observed that dissolving microneedles made from PVP-K90 and HPMC E50, incorporating Oryza sativa L. extract complex, showed enhanced transfollicular skin penetration and maintained safety for keratinocytes, with the P25H5 formulation demonstrating faster dissolution and greater effectiveness.
1 citations
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May 2022 in “Pharmaceutics” This study found that a developed nanostructured lipid carrier formulation of tea seed oil can effectively stimulate hair growth and reduce the oily feeling associated with direct application.
1 citations
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January 2014 This study found that Crataegus pinnatifida extract promoted hair growth in mice by inducing the anagen phase, potentially through activating signaling pathways that enhance cell survival.
In this study, six types of cold-pressed oils commonly found in the Polish market were analyzed for their health-promoting compounds and antioxidant activity, revealing them as valuable sources of bioactive compounds like polyunsaturated fatty acids, tocopherols, sterols, and polyphenols, without exceeding recommended deterioration parameters.
This study found that the nutraceutical product DERM decreased the pro-inflammatory cytokine IL-6 in mesenchymal stem cells under in vitro conditions.
37 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” This study found that Bokusoku extract and its compound pentagalloyl glucose inhibited testosterone metabolism and sebum synthesis, suggesting potential therapeutic use for androgen-related acne.