June 2024 in “Pharmacon Jurnal Farmasi Indonesia” In this study, researchers evaluated different formulations of a nanoemulsion combining candlenut oil and virgin coconut oil on male rats and found that a 1:3 ratio yielded significant hair growth results, with an average hair length of 17.14 mm and a weight of 699.37 mg.
December 2021 in “Trichology and cosmetology:” This study demonstrated that a daily oral supplement of 1000 mg Kera-Diet® improved hair and nail conditions in women experiencing acute telogen effluvium and brittle nail syndrome over three months.
27 citations
,
September 2017 in “Journal of Medicinal Food” In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.
1 citations
,
January 2010 in “Journal of Oriental Medicine” Black bean, wheat, and rice bran extracts can boost hair growth and improve hair quality.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review outlines the phytochemistry, preparation methods, and potential therapeutic benefits of fenugreek-based hair oil, suggesting its use for hair growth and scalp health, while emphasizing its safety and future prospects in cosmetics and pharmaceuticals.
Safflower extract in nanostructured carriers was more effective than minoxidil for hair growth without irritating skin.
This study found that low-temperature rendering of black beans, peony, and green tea extracts retains higher antioxidant properties and effectively supports scalp health by strengthening follicles and moisturizing the scalp.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review article summarizes the phytochemistry, preparation methods, applications, and potential therapeutic benefits of fenugreek-based hair oil, suggesting its use as a natural remedy for hair growth, scalp health, and conditioning, while also noting its safety and future potential in cosmetic and pharmaceutical formulations.
3 citations
,
April 2023 in “Quality Assurance and Safety of Crops & Foods” This study found that oil extracted from Prinsepia utilis seeds is physicochemically stable and suitable for use in manufacturing ketoconazole soap, which met quality control standards and may provide a cost-effective alternative to expensive additives in cosmetic and pharmaceutical applications.
1 citations
,
June 2022 in “Pakistan biomedical journal” This review discusses the potential benefits of converting pumpkin seeds, often considered industrial waste, into valuable nutrition-rich materials, but reports no new experimental results.
3 citations
,
August 2021 in “Journal of fiber science and technology” This study found that chitin nanofibrils prepared by the aqueous counter collision process exhibited superior emulsifying properties for stabilizing oil droplets in Pickering emulsions compared to cellulose nanofibrils.
December 2024 in “Tropical Journal of Natural Product Research” This study aimed to enhance the skin penetration of brown algae fucoidan using a Nanostructured Lipid Carrier, achieving a formulation with good physical quality and stability.
3 citations
,
December 2020 in “Pharmaceutical Sciences and Research” This study found that using 70% ethanol as a solvent for extracting unsoaked Leucaena leucocephala seeds produces a high extract yield while managing mimosine levels, indicating potential for nutraceutical use.
July 2022 in “International Journal of Applied Pharmaceutics” This study concluded that the optimized caffeine-loaded nanostructured lipid carriers improved hair growth by enhancing permeation through skin layers more effectively than an existing market formula.
10 citations
,
July 2019 in “Journal of Asia-Pacific Entomology” This study suggests that ultra-fine powders of steamed and lyophilized mature silkworms may have enhanced pharmacological effects compared to fine powders, possibly due to their smaller particle size.
August 2023 in “Journal of Student Research” This study found that incorporating keratin extracted from hair into NBR modestly enhanced the mechanical properties and biodegradability of the rubber.
2 citations
,
November 2019 in “Journal of Medicinal Food”
7 citations
,
January 2014 in “Biological & pharmaceutical bulletin” This study found that rice bran oil extracted by supercritical CO2 can be considered non-genotoxic based on in vitro and in vivo test results, despite some chromosomal aberrations observed under specific conditions.
December 2025 in “Jurnal Farmasi Tinctura” This study found that a hair tonic containing 15% ethanol extract of cocoa leaves effectively stimulated hair growth in rabbits, outperforming minoxidil 2%, and was safe with no skin irritation observed.
32 citations
,
December 2013 in “Biological & Pharmaceutical Bulletin” In this study, rice bran supercritical CO2 extract demonstrated potential to promote hair growth in mice, increasing hair follicles and growth factor expression, similarly to 3% minoxidil.
14 citations
,
July 2017 in “Pakistan Journal of Zoology” Fenugreek leaf extracts significantly promoted hair growth in mice with alopecia.
December 2010 in “Journal of Oriental Medicine” This study found that shampoos containing extracts from black bean, wheat, and rice bran enhanced hair growth activity and improved the physical properties of aged hair in laboratory models.
February 2026 in “IOP Conference Series Earth and Environmental Science” This study identified specific morphological characteristics and kinship relationships among 27 candlenut genotypes in Karo Regency, North Sumatra, highlighting variations in stem, leaf, flower, fruit, and kernel traits, with the closest relationship between MTB1 and MTB2 genotypes.
216 citations
,
September 2020 in “Scientific African” This review discusses the potential of pumpkin seeds as a functional food ingredient, highlighting their promising bioactive compounds and health benefits, but reports no new clinical results.
7 citations
,
March 2021 in “Evidence-based Complementary and Alternative Medicine” This study found that Nelumbinis Semen extract may promote hair growth and reduce hair loss by increasing VEGF and IGF-1 expression and decreasing TGF-β1 in human dermal papilla cells and mice.
54 citations
,
May 2017 in “Biomedicine & Pharmacotherapy” This review discusses the nutrient profile and potential health benefits of pumpkin and watermelon seeds, concluding they are underutilized and could be developed into various nutraceuticals.
18 citations
,
October 2013 in “EFSA Journal” The EFSA panel concluded that coriander seed oil is safe for use as a novel food ingredient at the proposed intake levels for healthy adults.
4 citations
,
July 1948 in “Experimental biology and medicine” This study found that continuous extraction of crude casein with hot ethanol reduced its nutritive quality and growth rates in rats, although liver supplementation restored normal growth.
42 citations
,
July 2014 in “European journal of pharmaceutics and biopharmaceutics” This study established a stable formulation for caffeine nanocrystals in specific solvent mixtures, which could be used to test their potential for enhanced hair follicle targeting and penetration.
7 citations
,
April 2011 in “Aktuelle Dermatologie” This study aimed to examine the effects of a nutritional formula containing fenugreek seed extract and micronutrients on androgenetic alopecia, but it reports no new clinical results.