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Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.

Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Jojoba oil is highly valued for its diverse medicinal and industrial uses.