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    Glossary Connective Tissue Sheath

    layer of fibrous tissue surrounding and supporting hair follicles

    The connective tissue sheath is a layer of fibrous tissue that surrounds and supports structures like hair follicles, muscles, and nerves. It provides structural integrity and protection, ensuring that these components are held in place and can function properly.

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    1. Dynamic ultrastructural changes of the connective tissue sheath of human hair follicles during hair cycle Archives of Dermatological Research · 1990 · 44 citations
    2. Removal of Intact Hair Papilla and Connective Tissue Sheath by Plucking Anagen Hairs**From the Department of Dermatology of the University of Hamburg, Germany. Journal of Investigative Dermatology · 1967 · 7 citations
    3. Connective tissue sheath of hair follicle is a major source of dermal type I procollagen in human scalp Journal of dermatological science · 2012 · 4 citations
    4. Single-cell transcriptomics reveals hair growth retardation mediated by aberrant connective tissue sheath contraction in male androgenetic alopecia Nature Communications · 2026
    5. Aberrant connective tissue sheath contraction drives premature hair follicle regression by inducing progenitor cell depletion in androgenetic alopecia bioRxiv (Cold Spring Harbor Laboratory) · 2023
    6. Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles Experimental dermatology · 2011 · 14 citations
    7. [A three-dimensional observation of human hair tissue treated by modified trypsin-HC1 method]. PubMed · 1989
    8. Neural crest cells give rise to non-myogenic mesenchymal tissue in the adult murid ear pinna bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 1 citations
    9. Growth of the Hair Physiological Reviews · 1954 · 521 citations
    10. Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control Journal of Investigative Dermatology · 2003 · 158 citations
    11. The Cytology and Cytochemistry of the Wool Follicle International review of cytology · 1979 · 90 citations
    12. Topographical and developmental studies on target sites of 1,25 (OH2) vitamin D3 in skin 1984 · 70 citations
    13. Hair follicle neogenesis induced by cultured human scalp dermal papilla cells Regenerative Medicine · 2009 · 63 citations
    14. 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla Archives of Dermatological Research · 1998 · 41 citations
    15. Hair follicle dermal stem cells and skin‐derived precursor cells: Exciting tools for endogenous and exogenous therapies Experimental Dermatology · 2017 · 30 citations
    16. Intermediate hair follicles: a new more clinically relevant model for hair growth investigations British Journal of Dermatology · 2010 · 30 citations
    17. Protective effects of taurine on human hair follicle grown <i>in vitro</i><sup>1</sup> International Journal of Cosmetic Science · 2006 · 26 citations
    18. Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors Stem cells translational medicine · 2016 · 17 citations
    19. Catagen in the hairless house mouse American Journal of Anatomy · 1967 · 17 citations
    20. Ability to culture dermal papilla cells from red deer (Cervus elaphus) hair follicles with differing hormonal responses in vivo offers a new model for studying the control of hair follicle biology 1996 · 16 citations
    21. Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goats Breed ˜The œanatomical record · 2015 · 7 citations
    22. Protease-Activated Receptor-1 (Thrombin Receptor) Is Expressed in Mesenchymal Portions of Human Hair Follicle Journal of Investigative Dermatology · 2003 · 7 citations
    23. Expression of SPARC (secreted protein acidic rich in cysteine) throughout the hair cycle in rats Adelaide Research & Scholarship (AR&S) (University of Adelaide) · 2004 · 1 citations
    24. [Osteopontin of skin and hair follicle of rat]. PubMed · 2000 · 1 citations
    25. Expression of melanocortin receptors on cutaneous fibroblastic cells – collagen and beyond Experimental Dermatology · 2005 · 1 citations
    26. 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas 2022
    27. 671 The adenosine-generating ecto-enzyme, CD73, functions as an intrafollicular regulator of human hair growth Journal of Investigative Dermatology · 2016
    28. Recognition of the ultrastructure of the hair follicle of Cashmere goats under the transmission electron microscope Chinese Veterinary Science · 2015
    29. Faculty Opinions recommendation of De novo production of dermal papilla cells during the anagen phase of the hair cycle. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2010
    30. Distribution of Type XII and XIV Collagens in Bovine Dermis and Hair Follicles Connective tissue · 2001