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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Minoxidil is better for female hair loss without hormonal issues, cyproterone acetate for those with; people with treated congenital heart disease have lower life quality; personality differs in types of infertility; oral terbinafine is best for toenail fungus; bladder training reduces incontinence; nurse clinics help with heart disease; weight loss improves body composition and liver disease; computer training cuts drug errors.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Hair microscopy is useful for diagnosing certain hair loss conditions but has limitations and must be interpreted carefully.

Surgeons need to understand natural hair patterns for better hair restoration results.

Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.

Chemical lumbar sympathectomy is an effective and safe treatment for idiopathic livedo reticularis.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Understanding causes and treatments helps doctors manage hair loss effectively.

Netherton syndrome can cause severe dehydration, infections, and growth issues in infants.

A woman with CHILD syndrome showed skin abnormalities, and the report suggests CHILD nevus and NEVIL might be the same condition, highlighting the need for diagnosis for genetic advice.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.

The document explains how to identify different hair problems using a microscope.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.