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Blocking YAP/TAZ could be a new way to treat skin cancer.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.

CCL5 is important for the hair growth potential of human dermal papilla cells.

Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.

Calcium signals and SHH guide the direction of feather growth in chicken skin.

Eating grape powder may reduce the severity of skin allergy symptoms.

Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.

Applying pseudoceramide improved skin and hair health.

Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.

Stem cells can create hair follicles, potentially treating permanent hair loss, and healthy skin and hair depend on mitochondrial function and special fats.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.

Porcine acellular dermal matrix treatment helps wounds heal faster and reduces scarring by affecting Jag1 in skin stem cells.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.